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Displaying results 3161 - 3170 of 7285 in total
  1. Drug

    Pixavir marboxil

    go.drugbank.com/drugs/DB21589
    Experimental

    Pixavir marboxil has a monoisotopic molecular weight of 540.12 Da. … Pixavir marboxil is a small molecule drug. The usage of the INN stem '-xavir' in the name indicates that Pixavir marboxil is a influenza CAP-dependent endonuclease inhibitor.

  2. Drug

    Crelosidenib

    go.drugbank.com/drugs/DB21642
    Investigational

    Crelosidenib has a monoisotopic molecular weight of 504.28 Da. … Crelosidenib is a small molecule drug.

  3. Drug

    Rosabulin

    go.drugbank.com/drugs/DB20161
    Investigational

    Rosabulin has a monoisotopic molecular weight of 400.1 Da. … Rosabulin is a small molecule drug. Rosabulin is under investigation in clinical trial NCT00276913 (A Phase I Study of STA-5312 in Subjects With Advanced or Metastatic Solid Tumors).

  4. Drug

    Velpatasvir

    go.drugbank.com/drugs/DB11613
    ApprovedInvestigational

    Velpatasvir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … Velpatasvir acts as a defective substrate for NS5A (Non-Structural Protein 5A), a non-enzymatic viral protein that plays a key role in Hepatitis C Virus replication, assembly, and modulation of host immune

  5. Drug

    Vonoprazan

    go.drugbank.com/drugs/DB11739
    ApprovedInvestigational

    Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations. … [A253702] In May 2022, the FDA approved the use of vonoprazan in a co-packaged product containing amoxicillin and clarithromycin for the treatment of _H. pylori_ infection.

  6. Drug

    Andexanet alfa

    go.drugbank.com/drugs/DB14562
    Approved

    Andexanet alfa is currently under regulatory review by the European Union and is undergoing clinical development in Japan [A35518]. … assemble the prothrombinase complex [A35558].

  7. Drug

    Amiodarone

    go.drugbank.com/drugs/DB01118
    ApprovedInvestigational

    Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings.

    Categories: BSEP/ABCB11 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexProducts: AMIODARON 200 1A PHARMA
  8. Drug

    Macitentan

    go.drugbank.com/drugs/DB08932
    ApprovedInvestigational

    Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013. … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October 2021 for the treatment of PAH.[L39105] It was subsequently approved by the FDA in March 2024.

    Categories: Endothelin A Receptor Antagonists
  9. Drug

    Ludaterone

    go.drugbank.com/drugs/DB21476
    Experimental

    Ludaterone is a small molecule drug. The usage of the INN stem '-terone' in the name indicates that Ludaterone is a antiandrogen. Ludaterone has a monoisotopic molecular weight of 380.14 Da.

  10. Drug

    Teslexivir

    go.drugbank.com/drugs/DB21202
    Experimental

    Teslexivir is a small molecule drug. The usage of the INN stem '-vir' in the name indicates that Teslexivir is a antiviral. Teslexivir has a monoisotopic molecular weight of 641.19 Da.