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Displaying results 311 - 320 of 10000 in total
  1. Drug

    Gramicidin D

    go.drugbank.com/drugs/DB00027
    ApprovedInvestigational

    Active against most Gram-positive bacteria and some Gram-negative organisms, Gramicidin D is used primarily as a topical antibiotic and is also found in Polysporin ophthalmic solution. … Gramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus

    Synonyms: Gramicidin A, Gramicidin BMixtures: Polysporin Burn Formula Cream, Polysporin Antibiotic Burn Cream
  2. Drug

    Mirtazapine

    go.drugbank.com/drugs/DB00370
    ApprovedInvestigational

    Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. … [T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy.

    Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine, 6-AzamianserinCategories: Cytochrome P-450 Substrates, Adrenergic alpha-2 Receptor Antagonists
  3. Drug

    NBI-98782

    go.drugbank.com/drugs/DB16905
    Approved

    Synonyms: (+)-A-Dihydrotetrabenazine, (2r,3r,11br)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2h-benzo(a)quinolizin-2-ol
  4. Drug

    Dordaviprone

    go.drugbank.com/drugs/DB14844
    ApprovedInvestigational

    Dordaviprone is a first-in-class small molecule imipridone. On August 6, 2025, dordaviprone was granted accelerated approval by the FDA. … [L53838] It is used to treat patients with diffuse midline glioma harboring an H3 K27M mutation.

    Synonyms: 7-benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo(1,2-A)pyrido(3,4-E)pyrimidin-5(4H)-one, 2,4,6,7,8,9-Hexahydro-4-((2-methylphenyl)methyl)-7-phenylmethyl)imidazo)(1,2-a)pyrido(3,4-e)pyrimidin-5(1H)-oneCategories: MATE 1 Inhibitors, MATE 2 Inhibitors
  5. Drug

    Ensifentrine

    go.drugbank.com/drugs/DB16157
    ApprovedInvestigational

    Ensifentrine is a first-in-class, selective dual inhibitor of the phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) enzymes. … [L50903] On June 26, 2024, the FDA announced the approval of an inhaled product of ensifentrine for the treatment of chronic obstructive pulmonary disease (COPD) in adults, which allows the drug to be

    Synonyms: N-(2-((2E)-9,10-DIMETOXI-4-OXO-2-((2,4,6-TRIMETILFENIL)IMINO)-6,7-DIHIDRO-2H-PIRIMIDO(6,1-A)ISOQUINOLEIN-3(4H)-IL)ETIL)UREA, UREA, N-(2-(6,7-DIHYDRO-9,10-DIMETHOXY-4-OXO-2-((2,4,6-TRIMETHYLPHENYL)IMINO)-2H-PYRIMIDO(6,1-A)ISOQUINOLIN-3(4H)-YL)ETHYL)-Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  6. Drug

    Recombinant human arylsulfatase A

    go.drugbank.com/drugs/DB17671
    Investigational

    Synonyms: Recombinant human arylsulfatase A, Recombinant human arylsulphatase A
  7. Drug

    A-dmDT390-bisFv(UCHT1)

    go.drugbank.com/drugs/DB16307
    Investigational

    A-dmDT390-bisFv(UCHT1) is under investigation in clinical trial NCT02943642 (Safety and Effectiveness of A-dmdt390-bisfv(ucht1) Fusion Protein in Subjects With Mycosis Fungoides).

    Synonyms: Anti-cd3 immunotoxin a-dmdt390-bisfv(ucht1)
  8. Drug

    N7-Methyl-Formycin A

    go.drugbank.com/drugs/DB02066
    Experimental

    Synonyms: N7-Methyl-Formycin A
  9. Drug

    6-methyl-formycin A

    go.drugbank.com/drugs/DB03986
    Experimental

    Synonyms: 6-methyl-formycin A, 2-(7-amino-6-methyl-3H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
  10. Drug

    Red blood cell-encapsulated L-asparaginase

    go.drugbank.com/drugs/DB17477
    Investigational

    It is being investigated in cancers.[L44923] … Red blood cell-encapsulated L-asparaginase is [Asparaginase Escherichia coli] encapsulated inside donor-derived red blood cells, which target cancer cells capable of altering asparagine and glutamine metabolism

    Synonyms: L-asparaginase encapsulated in red blood cells, asparaginase encapsulated in erythrocytes