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Amikacin
go.drugbank.com/drugs/DB00479ApprovedInvestigationalVet approvedof patients with the disease who do not respond to traditional treatment. … [FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A.
Products: AMBEL-TECEslicarbazepine acetate
go.drugbank.com/drugs/DB09119ApprovedInvestigationalEslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled … Eslicarbazepine acetate is marketed as Aptiom in North America and Zebinix or Exalief in Europe. It is available in 200, 400, 600, or 800mg tablets that are taken once daily, with or without food.
Meperidine
go.drugbank.com/drugs/DB00454ApprovedInvestigationalA narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. … Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromePemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalPemetrexed was first approved by the FDA in February 4, 2004.[A253907] … Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta.
Products: TEC PRED, PEMETREXED 500 MG POLVO LIOFILIZADO PARA SOLUCIÓN DE INFUSIÓN.Levomilnacipran
go.drugbank.com/drugs/DB08918ApprovedInvestigational[L47956] While levomilnacipran was previously investigated and proposed as a potential treatment for stroke in Europe, the EMA decided against this use.[L48011] … [A261181, A38560] Levomilnacipran is the more active 1S,2R-enantiomer in the racemate [milnacipran].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeIndacaterol
go.drugbank.com/drugs/DB05039ApprovedInvestigationalIt was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. … Indacaterol is also a chiral molecule but only the pure R-enantiomer is dispensed.
Categories: Agents to Treat Airway DiseaseFutibatinib
go.drugbank.com/drugs/DB15149ApprovedInvestigational[L43347] On July 4, 2023, the European Commission granted Conditional Marketing Authorization for futibatinib for the treatment of cholangiocarcinoma.[L47800] … [A253193,A253198] As a novel inhibitor of FGFR, futibatinib was first approved by the FDA in September 2022 to treat different types of intrahepatic cholangiocarcinoma.
Ulipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationaldebated due to ethical concerns related to abortion (Rosato et al, 2016). … Ulipristal is currently recommended as first line therapy for emergency contraception, due to improved efficacy and similar side effect profile as compared to the traditional use of levonorgestrel or the
Categories: Sex Hormones and Modulators of the Genital SystemProducts: ACETATO DE ULIPRISTALUnoprostone
go.drugbank.com/drugs/DB06826ApprovedWithdrawnUnoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate. The main indication of Unoprostane is treatment of glucoma.
Azithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalgroup at the 9a position on the aglycone ring, which allows for the prevention of its metabolism. … In March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine].
Products: ZITHROMAX TR-SAFT K B 25KG, AZYTER 15 MG/G TEK DOZLUK GOZ DAMLASI, 6 ADET