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Raxibacumab

Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012. … Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons.

Sertraline

Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. … Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine].

Paroxetine

[T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. … [L7712,L7715] A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters.

Cidofovir

Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. … [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since been discontinued.[L6223]

Arginine glutamate

Esterified estrogens

Esterified estrogens are a man-made mixture of estrogens that are used to treat symptoms of menopause such as hot flashes, vaginal dryness, vaginal burning or irritation, or other hormonal changes in the … It is being also for the prevention and treatment of osteoporosis.

Cenobamate

[A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively modulates GABA_A and inhibits voltage gated sodium channels. … Cenobamate, or YKP-3089, is an antiepileptic drug developed by SK Pharmaceuticals and used to treat partial onset seizures.

Quazepam

Quazepam is a trifluoroethyl benzodiazepine derivative. It was first approved in the US in 1985 and is used as a hypnotic for the treatment of insomnia. … [L44913] It appears to be unique amongst other benzodiazepine derivatives in its relatively high affinity for sleep-promoting α1 subunit-containing GABA_A receptors and low affinity for other

Maxy-G34

It is being developed by Maxygen, Inc. for the treatment of chemotherapy-induced neutropenia. … MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF).

Alosetron

Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. … In June 2002, the FDA approved a supplemental new drug application allowing the remarketing of the drug under restricted conditions of use.