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Eflornithine
go.drugbank.com/drugs/DB06243ApprovedInvestigationalWithdrawna 68% reduction in the risk of death were observed. … [A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or interacts with ras, both very well-known oncogenes, thus increasing the interest in targeting ornithine carboxylase as a
Synonyms: 2-(difluoromethyl)ornithine, α-difluoromethylornithineFluasterone
go.drugbank.com/drugs/DB06250ExperimentalHas antiproliferative effects on HIV-1 and reduces HIV-1 replication.
Thioctic acid tromethamine
go.drugbank.com/drugs/DB06253ExperimentalA salt of alpha-lipoic acid and tromethamine; may be useful in treating vascular stress in patients with diabetes.
Synonyms: (R)-5-(1,2-dithiolaln-3-yl)-pentanoic acid tromethaminerPSGL-Ig
go.drugbank.com/drugs/DB06256InvestigationalRecombinant P-selectin glycoprotein ligand IgG fusion protein (rPSGL-Ig) is a fusion protein of human P-selectin ligand and IgG1-Fc.
Synonyms: rPSGL-1-Ig, Recombinant soluble PSGL-1 Fc chimeraLonidamine
go.drugbank.com/drugs/DB06266InvestigationalLonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 1-(2,4-dichlorbenzyl)-indazole-3-carboxylic acidMAHDL01
go.drugbank.com/drugs/DB06270ExperimentalMAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio that improves overall cardiovascular health.
Maxacalcitol
go.drugbank.com/drugs/DB06272InvestigationalCategories: Vitamin D and Analogues, Compounds used in a research, industrial, or household settingAlvimopan
go.drugbank.com/drugs/DB06274ApprovedInvestigationalAlvimopan is a peripherally acting μ opioid antagonist. It is used to avoid postoperative ileus following small or large bowel resection and accelerates the gastrointestinal recovery period.
Categories: Heterocyclic Compounds, 1-Ring