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SJG-136
go.drugbank.com/drugs/DB11965InvestigationalSJG-136 has been used in trials studying the treatment of Recurrent Fallopian Tube Cancer, Secondary Acute Myeloid Leukemia, de Novo Myelodysplastic Syndromes, Recurrent Ovarian Epithelial Cancer, and Secondary Myelodysplastic Syndromes,...
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingBMS-986094
go.drugbank.com/drugs/DB11966InvestigationalINX-08189 has been used in trials studying the treatment of Hepatitis C, HCV (Genotype 1), and Hepatitis C Virus.
Categories: Heterocyclic Compounds, 2-RingBinimetinib
go.drugbank.com/drugs/DB11967ApprovedInvestigationalBinimetinib, also known as _Mektovi_, is a potent and selective oral mitogen-activated protein kinase 1/2 (MEK 1/2) inhibitor which is combined with [Encorafenib]. … combination of [Encorafenib] and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients with unresectable or metastatic melanoma with the BRAF V600E or V600K mutations, as
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: MEKTOVI® 15 MG TABLETAS RECUBIERTASUprosertib
go.drugbank.com/drugs/DB11969InvestigationalUprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others.
Categories: Heterocyclic Compounds, 1-RingVilaprisan
go.drugbank.com/drugs/DB11971InvestigationalVilaprisan has been used in trials studying the treatment of Leiomyoma and Clinical Trial, Phase I.
Golvatinib
go.drugbank.com/drugs/DB11977InvestigationalGolvatinib has been investigated for the treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck.
Categories: Heterocyclic Compounds, 1-Ring, Vascular Endothelial Growth Factor Receptor-2, antagonists & inhibitorsLetaxaban
go.drugbank.com/drugs/DB11984InvestigationalLetaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and Acute Coronary Syndrome.
Categories: Heterocyclic Compounds, 1-RingDapaconazole
go.drugbank.com/drugs/DB11985InvestigationalDapaconazole has been used in trials studying the treatment of Tinea Pedis.
Categories: Heterocyclic Compounds, 1-RingGSK-2018682
go.drugbank.com/drugs/DB11987InvestigationalGSK2018682 has been investigated for the treatment of Multiple Sclerosis, Relapsing-Remitting.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingPF-03463275
go.drugbank.com/drugs/DB11993InvestigationalPF-03463275 has been used in trials studying the treatment of Schizophrenia and Cognitive Impairments Associated With Schizophrenia.
Categories: Heterocyclic Compounds, 1-Ring