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Pirenzepine
go.drugbank.com/drugs/DB00670ApprovedWithdrawnIt promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. … It also potentiates the effect of other antiulcer agents such as cimetidine and ranitidine. It is generally well tolerated by patients.
Rosoxacin
go.drugbank.com/drugs/DB00817ApprovedRosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. … Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of parenteral administration seen with penicillin,
N-(2-Aminoethyl)-1-aziridineethanamine
go.drugbank.com/drugs/DB15643ExperimentalFirst described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease and its activity against Severe Ac...
Categories: Agents Acting on the Renin-Angiotensin SystemSomapacitan
go.drugbank.com/drugs/DB15093ApprovedInvestigational[A219146] Somapacitan was granted FDA approval on 28 August 2020.[L15666] … [A219126,L15661] This human growth hormone analog differs by the creation of an albumin binding site, and prolonging the effect so that it requires weekly dosing rather than daily.
Products: Sogroya® 5 mg/1.5 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet), Sogroya® 10 mg/1.5 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet)Chikungunya virus Senegal strain 37997 envelope protein E1
go.drugbank.com/drugs/DB21767ApprovedInvestigationalOne of three components of a recombinant Chikungunya virus vaccine called Vimkunya.
Anileridine
go.drugbank.com/drugs/DB00913ApprovedIllicitWithdrawnSome of their side effects are also caused by actions in the CNS.
Chlorzoxazone
go.drugbank.com/drugs/DB00356ApprovedIt is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Products: PARAFLEX 250 MG TABLET, 20 ADET, PARAFLEX 250 MG TABLET, 500 ADETMagnesium silicate
go.drugbank.com/drugs/DB13249ApprovedWithdrawnMagnesium silicate is a compound of magnesium oxide and silicon. It is the magnesium salt of silicic acid containing an unspecified amount of water. … [L2603] Under the FDA, magnesium silicate is determined as a member of the substances generally recognized as safe (GRAS) to be used as an anticaking agent.[L2605]
Idelalisib
go.drugbank.com/drugs/DB09054ApprovedInvestigationalTreatment of lymphoma cells with idelalisib has been shown to result in inhibition of chemotaxis and adhesion, and reduced cell viability. … type 4 signalling, which are involved in trafficking and homing of B-cells to the lymph nodes and bone marrow.
Omapatrilat
go.drugbank.com/drugs/DB00886ExperimentalThe inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating blood vessels, and reducing preload and ventricular remodeling.
Categories: Agents Acting on the Renin-Angiotensin System