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Displaying results 3241 - 3250 of 10000 in total
  1. Drug

    Measles virus vaccine live attenuated

    go.drugbank.com/drugs/DB10315
    ApprovedInvestigational

    Measles virus vaccine live attenuated is a live virus vaccine for simultaneous vaccination against measles, which is a common childhood disease. … The vaccine is prepared from the attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo cell culture.

    Synonyms: Measles virus live antigen, A
  2. Drug

    Agkistrodon piscivorus antivenin

    go.drugbank.com/drugs/DB13894
    Approved

    Approximately 99% of all venomous snake bites in the United States are caused by Crotalidae, also known as _pit vipers_. … As the only semi-aquatic viper species, cottonmouth snakes are strong swimmers and are frequently found in or near water [L2888]. This species of snake is endemic to the United States.

  3. Drug

    Arimoclomol

    go.drugbank.com/drugs/DB05025
    Approved

    Arimoclomol is a hydroxylamine derivative [A264414] and a heat-shock protein-70 (HSP70) co-inducer. … [L51384] Arimoclomol was approved by the FDA on September 20, 2024, making it the first treatment for Niemann-Pick disease, type C (NPC).

  4. Drug

    Alaproclate

    go.drugbank.com/drugs/DB13233
    Experimental

    Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s. … Development was discontinued due to concerns over hepatotoxicity observed in animal studies.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  5. Drug

    Mesulergine

    go.drugbank.com/drugs/DB21193
    Experimental

    Mesulergine is a small molecule drug. Mesulergine has a monoisotopic molecular weight of 362.18 Da.

    Categories: Heterocyclic Compounds with 4 or More Rings
  6. Drug

    Methoxamine

    go.drugbank.com/drugs/DB00723
    ApprovedInvestigationalWithdrawn

    An alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system.

  7. Drug

    Erdosteine

    go.drugbank.com/drugs/DB05057
    ApprovedInvestigational

    Erdosteine is a drug that causes a breakdown of mucus, also known as a _mucolytic_ agent. … Erdosteine is associated with a low incidence of adverse events, most of which are gastrointestinal and generally mild.

  8. Drug

    Inbakicept

    go.drugbank.com/drugs/DB16479
    Investigational

    It is one of the active ingredients in Anktiva, a combination product also containing [nogapendekin alfa], where a single inbakicept is complexed with two nogapendekin alfa components. … BCG) immunotherapy; however, NMIBC is associated with a risk of disease recurrence or progression into advanced disease despite initial treatment with BCG.

  9. Drug

    Alifedrine

    go.drugbank.com/drugs/DB20853
    Experimental

    Alifedrine is a small molecule drug. The usage of the INN stem '-drine' in the name indicates that Alifedrine is a sympathomimetic. Alifedrine has a monoisotopic molecular weight of 289.2 Da.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Mirdametinib

    go.drugbank.com/drugs/DB07101
    ApprovedInvestigational

    Mirdametinib is a mitogen-activated protein kinase (MAP2K, MEK, MAPKK) inhibitor. On February 11, 2025, mirdametinib was approved by the FDA for the treatment of neurofibromatosis type 1 (NF1). … [L52485] NF1 is an autosomal-dominant genetic condition caused by loss-of-function variants in the _NF1_ tumour suppressor gene,[A265065,A265070] leading to neurofibromin dysfunction and aberrant activation