Measles virus vaccine live attenuated

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Measles virus vaccine live attenuated is a vaccine used to prevent Measles.

Brand Names
M-M-R II, Proquad
Generic Name
Measles virus vaccine live attenuated
DrugBank Accession Number
DB10315
Background

Measles virus vaccine live attenuated is a live virus vaccine for simultaneous vaccination against measles, which is a common childhood disease. The vaccine is prepared from the attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo cell culture.

Type
Biotech
Groups
Approved, Investigational
Biologic Classification
Vaccines
Attenuated
Synonyms
  • Live attenuated measles virus (Schwartz strain)
  • Measles vaccine (live)
  • Measles virus live antigen
  • Measles virus live antigen, A
  • Measles virus strain enders' attenuated edmonston live (attenuated) antigen
  • Measles virus strain enders' attenuated edmonston live antigen
  • Measles virus vaccine live
  • Measles virus vaccine live attenuated
  • Measles Virus Vaccine Live, Enders' attenuated Edmonston strain
  • Measles virus vaccine, inactivated
  • Measles virus vaccine, live
  • Measles virus vaccine, live, attenuated
  • Measles virus vaccine,live attenuated

Pharmacology

Indication

Measles virus vaccine is used to prevent measles in combination with other virus vaccines, such as the rubella and Mumps virus vaccine.1,2

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination to preventMeasles•••••••••••••••••••••
Prevention ofRubeola•••••••••••••••••••••• ••••••• ••• ••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbataceptThe therapeutic efficacy of Measles virus vaccine live attenuated can be decreased when used in combination with Abatacept.
AdalimumabThe therapeutic efficacy of Measles virus vaccine live attenuated can be decreased when used in combination with Adalimumab.
AldesleukinThe therapeutic efficacy of Measles virus vaccine live attenuated can be decreased when used in combination with Aldesleukin.
AlefaceptThe therapeutic efficacy of Measles virus vaccine live attenuated can be decreased when used in combination with Alefacept.
AlemtuzumabThe therapeutic efficacy of Measles virus vaccine live attenuated can be decreased when used in combination with Alemtuzumab.
Food Interactions
Not Available

Products

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Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Measles Virus Vacc Live Att Freez Dried InjPowder, for solution1000 unit / vialSubcutaneousIaf Biovac Inc.1991-12-311997-08-20Canada flag
Measles Virus Vaccine Live Atten DriedPowder, for solution1000 unit / .5 mLSubcutaneousConnaught Laboratories Ltd.1982-12-312000-07-18Canada flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
M-M-R IIMeasles virus vaccine live attenuated (1000 [TCID_50]/0.5mL) + Mumps virus strain B level jeryl lynn live antigen (12500 [TCID_50]/0.5mL) + Rubella virus vaccine (1000 [TCID_50]/0.5mL)Injection, powder, lyophilized, for suspensionSubcutaneousA-S Medication Solutions1971-04-21Not applicableUS flag
M-M-R IIMeasles virus vaccine live attenuated (1000 TCID50/0.5mL) + Mumps virus strain B level jeryl lynn live antigen (12500 TCID50/0.5mL) + Rubella virus vaccine (1000 TCID50/0.5mL)Powder, for solutionSubcutaneousMerck Ltd.1979-12-31Not applicableCanada flag
M-M-R IIMeasles virus vaccine live attenuated (1000 [TCID_50]/0.5mL) + Mumps virus strain B level jeryl lynn live antigen (12500 [TCID_50]/0.5mL) + Rubella virus vaccine (1000 [TCID_50]/0.5mL)Injection, powder, lyophilized, for suspensionSubcutaneousPhysicians Total Care, Inc.1996-08-072012-06-30US flag
M-M-R IIMeasles virus vaccine live attenuated (1000 [TCID_50]/0.5mL) + Mumps virus strain B level jeryl lynn live antigen (12500 [TCID_50]/0.5mL) + Rubella virus vaccine (1000 [TCID_50]/0.5mL)Injection, powder, lyophilized, for suspensionSubcutaneousMerck Sharp & Dohme Llc1971-04-21Not applicableUS flag
M-M-R II VACCINEMeasles virus vaccine live attenuated (1000 CCID50/0.5mL) + Mumps virus strain B level jeryl lynn live antigen (12500 CCID50/0.5mL) + Rubella virus vaccine (1000 CCID50/0.5mL)Injection, powder, for solutionSubcutaneousMSD PHARMA (SINGAPORE) PTE. LTD.1988-06-24Not applicableSingapore flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
MFZ8I7277D
CAS number
Not Available

References

General References
  1. DailyMed: Proquad (measles, mumps, rubella, and varicella live vaccine) lyophilized powder for injection [Link]
  2. FDA Approved Drug Products: PRIORIX (Measles, Mumps, and Rubella Vaccine, Live), suspension for subcutaneous injection [Link]
PubChem Substance
347910494
RxNav
804179

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedPreventionBCG Infection / Immune Responses / Vaccine Reaction1
4CompletedPreventionHepatitis A Virus1
4CompletedPreventionHepatitis A / Measles / Mumps / Rubella / Varicella Zoster Virus Infection1
4CompletedPreventionJapanese Encephalitis / Measles / Mumps / Rubella1
4CompletedPreventionMeasles / Mumps / Rubella2

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, powder, lyophilized, for solutionSubcutaneous
Injection, powder, lyophilized, for suspensionSubcutaneous
Powder, for solutionSubcutaneous
Injection, powder, for solutionSubcutaneous1000 CCID50/0.5mL
Injection, powder, for suspensionIntramuscular; Subcutaneous
Injection, powder, lyophilized, for solutionSubcutaneous0.5 ml
Injection, powder, for solution1000 CCID_50/0.5ml
Powder, for solutionSubcutaneous1000 unit / vial
Powder, for solutionSubcutaneous1000 unit / .5 mL
Kit; liquid; powder, for solutionSubcutaneous
Liquid; powder, for solutionSubcutaneous
Injection, powder, for solutionSubcutaneous
Kit; powder, for solutionIntramuscular; Subcutaneous
Injection, solutionIntramuscular; Subcutaneous
Injection, powder, for solutionIntramuscular; Subcutaneous
Injection
Injection, powder, lyophilized, for solutionIntramuscular; Subcutaneous
Powder, for solutionIntramuscular; Subcutaneous
Injection, powder, lyophilized, for suspensionIntramuscular; Subcutaneous
Injection, powder, lyophilized, for suspensionSubcutaneous
InjectionSubcutaneous
Solution
Injection, powder, for solution
Injection, suspension1000 CCID_50/0.5ml
Injection, powder, lyophilized, for suspension
Powder
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at December 01, 2015 20:03 / Updated at February 25, 2024 21:03