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Displaying results 3251 - 3260 of 7452 in total
  1. Drug

    Flosequinan

    go.drugbank.com/drugs/DB13228
    ApprovedWithdrawn

    Flosequinan was approved in the USA and the UK for a year prior to being withdrawn from the market due to increased mortality in chronic heart failure patients, found in drug trials.[A174979,L43942]

  2. Drug

    Bucetin

    go.drugbank.com/drugs/DB13278
    ApprovedWithdrawn

    Bucetin is an analgesic and antipyretic medication which was approved for use in Germany but was withdrawn from the market in 1986 due to renal toxicity caused by the medication.[A175636]

  3. Drug

    Suprofen

    go.drugbank.com/drugs/DB00870
    ApprovedWithdrawn

    It is no longer approved for use in the United States.

  4. Drug

    ALTU-135

    go.drugbank.com/drugs/DB05330
    Investigational

    ALTU-135, the Company's orally administered enzyme replacement therapy for patients with pancreatic insufficiency, is manufactured by blending three drug substance enzymes: lipase, protease and amylase

  5. Drug

    LX201

    go.drugbank.com/drugs/DB04943
    Investigational

    The implant is being developed clinically for the prevention of rejection in corneal transplantation. It is being developed by Lux Biosciences, Inc.

  6. Drug

    Damoctocog alfa pegol

    go.drugbank.com/drugs/DB14700
    ApprovedInvestigational

    In order to extend half-lives, techniques such as fusion to protein conjugates (Fc part of IgG1 or albumin), chemical modification (PEGylation), and protein sequence modification have been utilized.

  7. Drug

    Cositecan

    go.drugbank.com/drugs/DB05806
    Investigational

    It has been developed for superior oral bioavailability and increased lactone stability. It is used to treat cancer.

  8. Drug

    TM5614

    go.drugbank.com/drugs/DB16516
    Investigational

    Further investigation of this compound is underway, including an exploratry Phase II study for its efficacy and safety for high-risk hospitalized patients with severe COVID-19 pneumonia[L31688].

    Categories: Experimental Unapproved Treatments for COVID-19
  9. Drug

    Tromantadine

    go.drugbank.com/drugs/DB13288
    Approved

    Tromantadine is marketed as Viru-Merz in the Czech Republic . It is an antiviral used in the treatment of herpes zoster and simplex.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  10. Drug

    Felodipine

    go.drugbank.com/drugs/DB01023
    Approved

    Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the infl...

    Categories: Antihypertensive Agents Indicated for Hypertension