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Voriconazole
go.drugbank.com/drugs/DB00582ApprovedInvestigationalVoriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. … [A236050] Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002.[L34660]
Synonyms: (αR,βS)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol, (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsBersiporocin
go.drugbank.com/drugs/DB18017InvestigationalSynonyms: (2r,3s)-2-(3-(4,5-dichloro-1h-benzo(d)imidazol-1-yl)propyl)piperidin-3-ol, 3-piperidinol, 2-(3-(4,5-dichloro-1h-benzimidazol-1-yl)propyl)-, (2r,3s)Ropanicant
go.drugbank.com/drugs/DB19134InvestigationalRopanicant is under investigation in clinical trial NCT06126497 (Study Evaluating Safety and Efficacy of Ropanicant in MDD Patients).
Synonyms: (1r,3s,5r)-3-(((6-chloropyridin-3-yl)oxy)methyl)-2-azabicyclo(3.1.0)hexane, 2-azabicyclo(3.1.0)hexane, 3-(((6-chloro-3-pyridinyl)oxy)methyl)-, (1r,3s,5r)-Peptide YY (3-36)
go.drugbank.com/drugs/DB05004InvestigationalPeptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity. It reduces appetite and increases satiety in obese patients.
Synonyms: PYY 3-36, PYY(3-36)Desflurane
go.drugbank.com/drugs/DB01189ApprovedInvestigationalDesflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as [methoxyflurane], [sevoflurane], [enflurane], or [isoflurane]. … It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888] Desflurane was granted FDA approval on 18 September 1992.[L30285]
Synonyms: 1,1,1,2-tetrafluoro-2-(difluoromethoxy)ethane, (±)-2-difluoromethyl 1,2,2,2-tetrafluoroethyl etherCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesBisphenol A diglycidyl ether
go.drugbank.com/drugs/DB14083ApprovedSynonyms: 2,2-Bis(4-glycidyloxyphenyl)propane, 2,2-bis(4'-glycidyloxyphenyl)propaneGemeprost
go.drugbank.com/drugs/DB08964ApprovedWithdrawnGemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion.
Synonyms: 16,16-Dimethyl-trans-delta-2-PGE1 methyl ester, 16,16-Dimethyl-trans-delta(sup 2)-prostaglandin E1 methyl esterCategories: Prostaglandins E, Prostaglandins E, SyntheticBusulfan
go.drugbank.com/drugs/DB01008ApprovedInvestigationalBusulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. … According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 1, 4-Bis[methanesulfonoxy]butane3-Hydroxyimino Quinic Acid
go.drugbank.com/drugs/DB03739ExperimentalSynonyms: 3-Hydroxyimino Quinic AcidS-(3-Iodobenzyl)glutathione
go.drugbank.com/drugs/DB04341ExperimentalSynonyms: S-(3-Iodobenzyl)glutathione