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Displaying results 3281 - 3290 of 10000 in total
  1. Drug

    Isatuximab

    go.drugbank.com/drugs/DB14811
    ApprovedInvestigational

    Isatuximab (formerly SAR650984) is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line. … [L12099] It is a cytolytic antibody targeted against CD38, a glycoprotein found on the surface of some immune cells that is highly expressed by malignant plasma cells in multiple myeloma.

    Products: SARCLİSA 100 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, SARCLİSA 500 MG/25 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET
  2. Drug

    4'-Methylene-5,8,10-trideazaaminopterin

    go.drugbank.com/drugs/DB05616
    Investigational

    CH-1504 is a an antirheumatic agent that has been shown in vitro to be a nonpolyglutamylatable and nonhydroxylatable antifolate that is more efficiently taken up into cells by the reduced folate carrier … It has been investigated for the treatment of Rheumatoid Arthritis (phase II).

    Categories: Heterocyclic Compounds, 2-RingInternational brands: M-Trex
  3. Drug

    beta-Alanine

    go.drugbank.com/drugs/DB03107
    Investigational

    A rare genetic disorder, hyper-beta-alaninemia, has been reported. … Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID.

    Synonyms: β-alanine, 3-aminopropanoic acid
  4. Drug

    Adecatumumab

    go.drugbank.com/drugs/DB05006
    Investigational

    Adecatumumab is a recombinant human monoclonal antibody of the IgG1 subclass with a binding specificity to epithelial cell adhesion molecule (EpCAM). … EpCAM (CD326) is a cell surface protein that is frequently expressed at high level on most solid tumor types, including prostate, breast, colon, gastric, ovarian, pancreatic and lung cancer.

  5. Drug

    Sirukumab

    go.drugbank.com/drugs/DB11803
    Investigational

    Sirukumab has been used in trials studying the treatment and basic science of Giant Cell Arteritis and Arthritis, Rheumatoid.

  6. Drug

    AZD-5672

    go.drugbank.com/drugs/DB11804
    Investigational

    Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis.

    Categories: CCR5 Receptor Antagonists
  7. Drug

    Dalotuzumab

    go.drugbank.com/drugs/DB11840
    Investigational

    Dalotuzumab has been investigated for the treatment of Breast Cancer, Non Small Cell Lung Cancer, and Metastatic Colorectal Cancer.

  8. Drug

    SAR422459

    go.drugbank.com/drugs/DB17908
    Investigational

    SAR422459 is a Lentiviral Vector Containing The Human Abca4 Gene that is currently being investigated to treat Stargardt disease.

  9. Drug

    Tributyrin

    go.drugbank.com/drugs/DB12709
    Investigational

    Tributyrin has been used in trials studying the treatment of Prostate Cancer and Unspecified Adult Solid Tumor, Protocol Specific.

  10. Drug

    Indoximod

    go.drugbank.com/drugs/DB12827
    Investigational

    Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.

    Synonyms: (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, 1-methyl-D-tryptophan