Sirukumab

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Sirukumab
Accession Number
DB11803
Description

Sirukumab has been used in trials studying the treatment and basic science of Giant Cell Arteritis and Arthritis, Rheumatoid.

Type
Biotech
Groups
Investigational
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
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Protein Chemical Formula
Not Available
Protein Average Weight
Not Available
Sequences
Not Available
Synonyms
Not Available

Pharmacology

Indication
Not Available
Contraindications & Blackbox Warnings
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbataceptThe risk or severity of adverse effects can be increased when Abatacept is combined with Sirukumab.
AbciximabThe risk or severity of adverse effects can be increased when Abciximab is combined with Sirukumab.
AdalimumabThe risk or severity of adverse effects can be increased when Adalimumab is combined with Sirukumab.
Adenovirus type 7 vaccine liveThe risk or severity of infection can be increased when Adenovirus type 7 vaccine live is combined with Sirukumab.
AldesleukinThe risk or severity of adverse effects can be increased when Aldesleukin is combined with Sirukumab.
AlefaceptThe risk or severity of adverse effects can be increased when Alefacept is combined with Sirukumab.
AlemtuzumabThe risk or severity of adverse effects can be increased when Alemtuzumab is combined with Sirukumab.
AlirocumabThe risk or severity of adverse effects can be increased when Alirocumab is combined with Sirukumab.
AltretamineThe risk or severity of adverse effects can be increased when Altretamine is combined with Sirukumab.
AmsacrineThe risk or severity of adverse effects can be increased when Amsacrine is combined with Sirukumab.
Additional Data Available
  • Extended Description
    Extended Description
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  • Severity
    Severity
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  • Evidence Level
    Evidence Level
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  • Action
    Action
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Food Interactions
Not Available

Categories

ATC Codes
L04AC15 — Sirukumab
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available

Chemical Identifiers

UNII
640443FU93
CAS number
1194585-53-9

References

General References
Not Available
PubChem Substance
347911243
Wikipedia
Sirukumab

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3CompletedTreatmentRheumatoid Arthritis5
3TerminatedTreatmentGiant Cell Arteritis (GCA)1
3WithdrawnTreatmentPolymyalgia Rheumatica1
2CompletedTreatmentMajor Depressive Disorder (MDD)1
2CompletedTreatmentRheumatoid Arthritis1
2RecruitingTreatmentNovel Coronavirus Infectious Disease (COVID-19) / Severe or Critical Confirmed Coronavirus Disease (COVID)-191
2WithdrawnTreatmentAsthma1
1CompletedNot AvailableHealthy Volunteers1
1CompletedBasic ScienceRheumatoid Arthritis1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on October 20, 2016 14:49 / Updated on June 12, 2020 10:53

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