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Displaying results 321 - 330 of 10000 in total
  1. Drug

    Fosfomycin

    go.drugbank.com/drugs/DB00828
    ApprovedInvestigational

    [A230348] Due to its ease of administration as a single 3-gram oral dose and desirable safety profile, fosfomycin has largely become a first-line therapeutic option for the treatment of uncomplicated … [A230348] In terms of chemical structure, fosfomycin is a phosphoenolpyruvate analog and contains a phosphonic group and an epoxide ring.

    Synonyms: L-cis-1,2-epoxypropylphosphonic acidProducts: FOSFOMICINA EG, Fosfomycin Infectopharm 40 mg/ml Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  2. Drug

    Aceclofenac

    go.drugbank.com/drugs/DB06736
    Approved

    It is a more commonly prescribed drug in Europe. … In 1991, aceclofenac was developed as an analog of a commonly prescribed NSAID, [DB00586], via chemical modification in effort to improve the gastrointestinal tolerability of the drug.

    Products: ACECLOFENAC EG
  3. Drug

    Orphenadrine

    go.drugbank.com/drugs/DB01173
    ApprovedInvestigational

    A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

    Synonyms: N,N-Dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamine, N,N-dimethyl-2-(phenyl(o-tolyl)methoxy)ethanamineProducts: Orphenadrine Citrate ER
  4. Drug

    Phentermine

    go.drugbank.com/drugs/DB00191
    ApprovedIllicitInvestigational

    Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug. … [A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as a new alternative that required lower doses of phentermine to obtain the desired effect.[A174373]

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: Phentermine Resin ER
  5. Drug

    Zuclopenthixol

    go.drugbank.com/drugs/DB01624
    ApprovedInvestigational

    These are organic polycyclic compounds containing a thioxanthene moiety, which is an aromatic tricycle derived from xanthene by replacing the oxygen atom with a sulfur atom. … Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.

    Products: CLOPIXOL DEPOT ENJ. 200 MG/ML IM SOLÜSYON, 1 ML, CLOPIXOL ACUPHASE 50 MG/ML IM ENJ. SOLUSYON, 1 ML
  6. Drug

    Benazepril

    go.drugbank.com/drugs/DB00542
    ApprovedInvestigational

    Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].

    Mixtures: BENAZEPLUS AL 20MG/25MG, BENAZEPLUS AL 10MG/12.5MGCategories: Agents Acting on the Renin-Angiotensin System
  7. Drug

    Felodipine

    go.drugbank.com/drugs/DB01023
    Approved

    It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins, exhibits competitive antagonism of the mineralcorticoid receptor, inhibits the activity of calmodulin-dependent

    International brands: Felodur ER, Plendil ERProducts: PLENDIL 2.5MG ER TABLET, PLENDIL 5 ER TABLETS (9MM)
  8. Drug

    Midodrine

    go.drugbank.com/drugs/DB00211
    ApprovedInvestigational

    An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.

    Synonyms: (±)-2-amino-N-(β-hydroxy-2,5-dimethoxyphenethyl)acetamide, 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamideProducts: MIDODRINA EG
  9. Drug

    Albuterol

    go.drugbank.com/drugs/DB01001
    ApprovedInvestigationalVet approved

    Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. … Salbutamol is formulated as a racemic mixture of the R- and S-isomers.

    Mixtures: Combivent nebuliser solution in unit dose vial, SALBUTAMOLO E IPRATROPIO BROMURO EGProducts: SACRUSYT® LA SALBUTAMOL 100 MCG / 200 DOSIS( SIN ALCOHOL), SALBUTAMOL AL N 200ED
  10. Drug

    Tranexamic acid

    go.drugbank.com/drugs/DB00302
    ApprovedInvestigational

    Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding. … [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986.[L31858]

    Products: ACIDO TRANEXAMICO EG, TRANSAMINE 50 MG/ML IV ENJ COZELTI, 5 ML