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Benactyzine
go.drugbank.com/drugs/DB09023ApprovedWithdrawnBenactyzine is an anticholinergic drug used as an antidepressant in the treatment of depression and associated anxiety. … Benactyzine is no longer widely used in medicine, although it is still a useful drug for scientific research. It does not possess any antihistamine properties.
Pizotifen
go.drugbank.com/drugs/DB06153ApprovedPizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management of migraines. … Sandomigran is available in a number of countries but is not approved by the FDA nor EMA.
Imetelstat
go.drugbank.com/drugs/DB14909ApprovedInvestigational[A187838] Imetelstat received FDA approval in June 2024 for use in certain patients with MDS who have transfusion-dependent anemia and are unable to use ESAs.[L50883,L50888] … Imetelstat is a first-in-class 18-amino acid oligonucleotide that directly and competitively inhibits human telomerase.
Dimethylthiambutene
go.drugbank.com/drugs/DB01444ExperimentalIllicitDimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid analgesic drug. … It is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential, although little more information is available.
Synonyms: N,N,1-trimethyl-3,3-di-2-thienylallylamine, N,N-dimethyl-4,4-di(2-thienyl)-3-buten-2-amineTromantadine
go.drugbank.com/drugs/DB13288ApprovedTromantadine is marketed as Viru-Merz in the Czech Republic [L5740]. It is an antiviral used in the treatment of herpes zoster and simplex.
Trinitrotoluene
go.drugbank.com/drugs/DB01676ExperimentalTrinitrotoluene is an explosive chemical that can cause skin irritation and other toxic consequences.
Categories: Compounds used in a research, industrial, or household settingVidarabine
go.drugbank.com/drugs/DB00194ApprovedWithdrawnIt has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the
Almonertinib
go.drugbank.com/drugs/DB16640ApprovedInvestigational[A231859] On March 19, 2020, almonertinib was approved in China for the treatment of EGFR T790M+ non-small cell lung cancer.[A231864] Almonertinib was also approved by the EMA on February 20, 2026.
Synonyms: 2-Propenamide, N-[5-[[4-(1-cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-, N-[5-[[4-(1-Cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-2-propenamidePimethixene
go.drugbank.com/drugs/DB13292ApprovedPimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. It is an anticholinergic used in the treatment of bronchitis.
Tideglusib
go.drugbank.com/drugs/DB12129ApprovedInvestigationalWithdrawnTideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy. It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inh...