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Displaying results 3321 - 3330 of 7284 in total
  1. Drug

    Brivaracetam

    go.drugbank.com/drugs/DB05541
    ApprovedInvestigational

    Briviact received FDA approval on February 19, 2016 [L760]. … Brivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam [A19184].

  2. Drug

    Luliconazole

    go.drugbank.com/drugs/DB08933
    ApprovedInvestigational

    It was approved by the FDA (USA) in November 2013 and is marketed under the brand name Luzu. Luliconazole is also approved in Japan. … Luliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes.

  3. Drug

    Temsirolimus

    go.drugbank.com/drugs/DB06287
    ApprovedInvestigational

    Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007. … Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  4. Drug

    Vemtoberant

    go.drugbank.com/drugs/DB21607
    Investigational

    Vemtoberant has a monoisotopic molecular weight of 619.2 Da. … Vemtoberant is a small molecule drug.

  5. Drug

    Delocamten

    go.drugbank.com/drugs/DB21711
    Investigational

    Delocamten has a monoisotopic molecular weight of 377.16 Da. … Delocamten is a small molecule drug.

  6. Drug

    Testosterone cypionate

    go.drugbank.com/drugs/DB13943
    ApprovedInvestigational

    It was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979. … Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester.

  7. Drug

    Melogliptin

    go.drugbank.com/drugs/DB20789
    Experimental

    Melogliptin has a monoisotopic molecular weight of 320.18 Da. … Melogliptin is a small molecule drug. The usage of the INN stem '-gliptin' in the name indicates that Melogliptin is a dipeptidyl aminopeptidase-IV inhibitor.

  8. Drug

    Lagociclovir

    go.drugbank.com/drugs/DB21266
    Experimental

    Lagociclovir has a monoisotopic molecular weight of 269.09 Da. … Lagociclovir is a small molecule drug. The usage of the INN stem '-ciclovir' in the name indicates that Lagociclovir is a antiviral, bicyclic heterocycle compound.

  9. Drug

    Garvagliptin

    go.drugbank.com/drugs/DB21280
    Experimental

    Garvagliptin has a monoisotopic molecular weight of 399.14 Da. … Garvagliptin is a small molecule drug. The usage of the INN stem '-gliptin' in the name indicates that Garvagliptin is a dipeptidyl aminopeptidase-IV inhibitor.

  10. Drug

    Cimpuciclib

    go.drugbank.com/drugs/DB21499
    Experimental

    Cimpuciclib has a monoisotopic molecular weight of 542.29 Da. … Cimpuciclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Cimpuciclib is a cyclin dependant kinase inhibitor.