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Displaying results 3331 - 3340 of 10000 in total
  1. Drug

    Diclofenac

    go.drugbank.com/drugs/DB00586
    ApprovedInvestigationalVet approved

    [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. … Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).

    Synonyms: [2-(2,6-dichloroanilino)phenyl]acetic acid, 2-((2,6-dichlorophenyl)amino)benzeneacetic acidInternational brands: Nu-Diclo
  2. Drug

    OXI-4503

    go.drugbank.com/drugs/DB05143
    Investigational

    OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular disrupting agent (VDA). … Preclinical studies have demonstrated that OXI-4503 has (i) single-agent activity against a range of xenograft tumor models; and (ii) synergistic or additive effects when incorporated in various combination

    Synonyms: Combretastatin A-1 bis(phosphate), Combretastatin A1 diphosphate
  3. Drug

    Cotsiranib

    go.drugbank.com/drugs/DB18404
    Investigational

    Synonyms: STP705 (small interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and cyclo-oxygenase-2 (COX-2))
  4. Drug

    Caricotamide

    go.drugbank.com/drugs/DB18950
    Investigational

    Caricotamide is under investigation in clinical trial NCT00746590 (Study of Anti-tumour Effects and Safety of Prolarix™ in Hepatocellular Carcinoma).

    Synonyms: 1-(2-amino-2-oxoethyl)-1,4-dihydropyridine-3-carboxamide
  5. Drug

    Avadomide

    go.drugbank.com/drugs/DB14857
    Investigational

    Avadomide is under investigation in clinical trial NCT02031419 (Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 3-(5-Amino-2-methyl-4-oxo-4H-quinazolin-3-yl)piperidine-2,6-dione
  6. Drug

    Lutikizumab

    go.drugbank.com/drugs/DB16224
    Investigational

    Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).

    Synonyms: Immunoglobulin, anti-(interleukin 1.beta./interleukin 1.alpha.) (synthetic human a-1234138 heavy chain), disulfide with synthetic human a-1234138 light chain, dimer
  7. Drug

    Doranidazole

    go.drugbank.com/drugs/DB17304
    Experimental

    Synonyms: (2rs,3sr)-3-((2-nitroimidazol-1-yl)methoxy)butane-1,2,4-triol, 1,2,4-butanetriol, 3-((2-nitro-1h-imidazol-1-yl)methoxy)-, (2r,3s)-rel-Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    PXS-5505

    go.drugbank.com/drugs/DB17510
    Investigational

    Synonyms: 2-buten-1-amine, 3-fluoro-4-(8-quinolinylsulfonyl)-, (2z)-
  9. Drug

    Luminol

    go.drugbank.com/drugs/DB18536
    Experimental

    Synonyms: 5-amino-2,3-dihydro-1,4-phthalazinedione, 3-aminophthalic hydrazideCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  10. Drug

    CAM-GM201

    go.drugbank.com/drugs/DB17687
    Experimental

    Synonyms: rAAV2/1 Hex alpha and beta, Recombinant adeno-associated viral vector serotype 2/1 encoding human beta-hexosaminidase alpha and beta subunits