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Solute carrier family 22 member 10
go.drugbank.com/bio_entities/BE0003652TransporterHumansPolypeptides: Solute carrier family 22 member 10Synonyms: Organic anion transporter 5Cytochrome b-c1 complex subunit 10
go.drugbank.com/bio_entities/BE0003859TargetHumansComponent of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit...
Polypeptides: Cytochrome b-c1 complex subunit 10Synonyms: Complex III subunit 10Perazine
go.drugbank.com/drugs/DB12710ApprovedWithdrawnPerazine has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
Categories: Heterocyclic Compounds, 3-RingProducts: PERAZIN-NEURAX 100 MG, PERAZIN-NEURAX 25 MGDabrafenib
go.drugbank.com/drugs/DB08912ApprovedInvestigationalDabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway.
Categories: Heterocyclic Compounds, 1-Ring, Organic Anion Transporter 1 InhibitorsProducts: TAFINLAR (CAPSULES 50 MG), TAFINLAR 50 MG KAPSUL, 20 ADETDrospirenone
go.drugbank.com/drugs/DB01395ApprovedInvestigationalSome studies have demonstrated a significantly increased risk and some demonstrating no risk of thromboembolic events. … Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with [Ethinyl estradiol].
Synonyms: 6β,7β;15β,16β-Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactoneMixtures: Angeliq 1 mg/2 mg Filmtabletten, ANGELIQ 1 MG/2 MG FILM KAPLI TABLET, 28 ADETThalidomide
go.drugbank.com/drugs/DB01041ApprovedInvestigationalWithdrawnIt has been reintroduced and used for a number of inflammatory disorders and cancers. … Thalidomide displays immunosuppressive and anti-angiogenic activity through modulating the release of inflammatory mediators like tumor necrosis factor-alpha (TNF-a) and other cytokine action.
Synonyms: α-N-phthalylglutaramide, (+-)-N-(2,6-dioxo-3-Piperidyl)phthalimideInternational brands: Pro-ban M, K-1710 kDa heat shock protein, mitochondrial
go.drugbank.com/bio_entities/BE0009028TargetHumansCo-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of...
Polypeptides: 10 kDa heat shock protein, mitochondrialSynonyms: Chaperonin 10, 10 kDa chaperoninTaste receptor type 2 member 10
go.drugbank.com/bio_entities/BE0020463TargetHumansGustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5
Polypeptides: Taste receptor type 2 member 10Simeprevir
go.drugbank.com/drugs/DB06290ApprovedWithdrawnor longer to 12 or 24 weeks [A19630] depending on prior response status and presence of HIV-1 co-infection. … The SVR12 was 83% (29/35) in treatment-naïve patients and 86% (19/22) in relapsing patients.
Categories: Genito Urinary System and Sex Hormones, Gynecological Antiinfectives and AntisepticsProducts: OLYSIO 150 MG KAPSUL ,KAPSUL, 28 ADETPotassium acetate
go.drugbank.com/drugs/DB14498ApprovedMixtures: Normosol-M and Dextrose, Normosol-M and DextroseCategories: Blood and Blood Forming Organs, Blood Substitutes and Perfusion Solutions