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Spinosad

Spinosad is a pediculicide mixture of spinosyn A and spinosyn D (in an approximately 5:1 ratio, respectively) used in the topical treatment of head lice in children (four years old and older) and in adults … Spinosad is an insecticide based on a compound found in S. spinosa, a bacterial species.

Enzastaurin

Enzastaurin, an investigational, targeted, oral agent, will be evaluated at more than 100 sites worldwide for the treatment of relapsed glioblastoma multiforme (GBM), an aggressive and malignant form of

Sulthiame

Pimicotinib

[L53748] Pimicotinib was granted Fast Track Designation in December 2023 by the FDA. [L53753]

Exisulind

Metyrosine

An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines.

Obinepitide

These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS.

Maprotiline

Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and...

N-(2-Aminoethyl)-1-aziridineethanamine

First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease

T-5224

T-5224 is an investigational drug developed to treat Sepsis-induced Acute Kidney Injury. It's mechanism of action is to inhibit c-Fos/activator protein-1.