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Medifoxamine
go.drugbank.com/drugs/DB13219ApprovedMedifoxamine was marketed as an atypical antidepressant, with anxiolyitc properties in France, Spain, and Morrocco in the 1990s but was later withdrawn from the market due to it causing cases of hepatotoxicity
MF101
go.drugbank.com/drugs/DB05052InvestigationalMF101 is a novel estrogen receptor beta (ERβ) selective agonist and unlike currently available hormone therapies, does not activate the estrogen receptor alpha (ERα), known to be implicated in tumor formation … MF101 is an oral drug designed for the treatment of hot flashes and night sweats in peri-menopausal and menopausal women.
Emeramide
go.drugbank.com/drugs/DB12192InvestigationalEmeramide has been used in trials studying the treatment of Mercury Poisoning.
Categories: Compounds used in a research, industrial, or household settingEnavogliflozin
go.drugbank.com/drugs/DB18970InvestigationalEnavogliflozin is under investigation in clinical trial NCT06399835 (Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis).
Categories: Drugs Used in DiabetesBrecanavir
go.drugbank.com/drugs/DB04887InvestigationalIn December of 2006 GSK announced a decision to discontinue the development of brecanavir for the treatment of HIV. The decision was based on issues regarding the formulation of the drug. … In July 2006, Vertex indicated that it expected GSK to initiate phase III trials of the drug in 2007.
Affitope AD01
go.drugbank.com/drugs/DB06086InvestigationalAD01 is a short peptide (7 amino acids in length) that induces Aß-targeting antibodies, therefore lowering Aß aggregates. … Affitope AD01 is an investigational drug developed for immunization to treat Alzheimer's Disease.
Pimethixene
go.drugbank.com/drugs/DB13292ApprovedPimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. It is an anticholinergic used in the treatment of bronchitis.
OSI-930
go.drugbank.com/drugs/DB05913InvestigationalIn preclinical studies, OSI-930 shows broad efficacy in tumor models representative of small cell lung cancer, glioblastoma, colorectal, renal, head and neck, non-small cell lung cancer and gastric cancers … OSI-930 is designed to target both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors.
Sulopenem etzadroxil
go.drugbank.com/drugs/DB16335ApprovedInvestigational[L51858] It is administered in combination with [probenecid] in order to increase antibiotic exposure.[L51768] … Sulopenem etzadroxil is a prodrug of the penem antibacterial [sulopenem]. Like other beta-lactam antibacterials, it is a time-dependent inhibitor of bacterial cell wall synthesis.
Chamomile
go.drugbank.com/drugs/DB14357ApprovedChamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Matricaria Recutita L. Flower