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Talquetamab
go.drugbank.com/drugs/DB16678ApprovedInvestigationalTalquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm c...
MVC-COV1901
go.drugbank.com/drugs/DB15854InvestigationalAs of September 2020, the vaccine candidate is in Phase 1 clinical trials to assess its safety and immunogenicity (NCT04487210). … Medigen has combined forces with Dynavax, which offers an advanced adjuvant, CpG 1018 (also known as [ISS-1018]), for use with its vaccine.
AGuIX
go.drugbank.com/drugs/DB18189InvestigationalIt is under development as a radiosensitizer to be used during radiation treatment of malignant glioma.
Cositecan
go.drugbank.com/drugs/DB05806InvestigationalCositecan is the novel camptothecin derivative which is also known as Karenitecin. It has been developed for superior oral bioavailability and increased lactone stability. It is used to treat cancer.
Benazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure . Upon cleavage of its ester group by the liver, benazepril is converted into its acti...
Aprepitant
go.drugbank.com/drugs/DB00673ApprovedInvestigationalAprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting associated with initial and r...
Unoprostone
go.drugbank.com/drugs/DB06826ApprovedWithdrawnUnoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate....
Pefloxacin
go.drugbank.com/drugs/DB00487ApprovedA synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
Tetraethylammonium
go.drugbank.com/drugs/DB08837InvestigationalAs an experimental agent, tetraethylammonium is used in its salt forms such as tetraethylammonium chloride and tetraethylammonium bromide. … The most common use of tetraethylammonium presently is as a pharmacological research agent that blocks selective potassium channels.
Bleomycin A6
go.drugbank.com/drugs/DB12992InvestigationalBleomycin A6 (also known as boanmycin) has been used in trials studying the treatment of Squamous Cell Lung Cancer. It was developed in China as an antineoplastic antibiotic.