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Carteolol
go.drugbank.com/drugs/DB00521ApprovedA beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
Categories: Beta Blocking Agents, Non-SelectiveCefoperazone
go.drugbank.com/drugs/DB01329ApprovedInvestigationalWithdrawnIt is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis … While its clinical use has been discontinued in the U.S., cefoperazone is available in several European countries most commonly under the product name, Sulperazon.
Synonyms: (6R,7R)-7-((R)-2-(4-Ethyl-2,3-dioxo-1-piperazinylcarboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl-1H-tetrazol-5-yl)thiomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeureTMC-310911
go.drugbank.com/drugs/DB15623Investigational[L12045,A191643] TMC-310911 is currently being investigated, in combination with other HIV therapies and antivirals, as a potential treatment for COVID-19 caused by SARS-CoV-2.[L12012] … TMC-310911 has shown marked activity against a variety of HIV-1 strains, including multi-PI-resistant strains, and may be less likely to generate resistance, making it a potentially desirable therapy for
Omaveloxolone
go.drugbank.com/drugs/DB12513ApprovedInvestigationalTherefore, the use of Nrf2 activators such as omaveloxolone represents a therapeutic advantage in this group of patients. … [L51654], [L52595] The use of omaveloxolone for the treatment of conditions involving mitochondrial dysfunction and oxidative stress has also been evaluated.[A257534,A257559]
Synonyms: Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-Ammonium molybdate
go.drugbank.com/drugs/DB11128InvestigationalAmmonium molybdate is a source of molybdenum that exists in several hydrate forms. It is intravenously administered as an additive to solutions for Total Parenteral Nutrition (TPN). … Molybdenum is an essential element that is present in enzymes including xanthine oxidase, sulfite oxidase, and aldehyde oxidase.
Categories: Compounds used in a research, industrial, or household settingNogalamycin
go.drugbank.com/drugs/DB20882ExperimentalThe usage of the INN stem '-mycin' in the name indicates that Nogalamycin is a antibiotic, produced by Streptomyces strain. Nogalamycin has a monoisotopic molecular weight of 787.31 Da.
Categories: Compounds used in a research, industrial, or household settingDAR-0100A
go.drugbank.com/drugs/DB16139InvestigationalDAR-0100A is under investigation in clinical trial NCT01466205 (Clinical Testing of a D1 Agonist for Cognitive Enhancement in Schizotypal Personality Disorder).
Categories: Dopamine D1 Receptor AgonistsPractolol
go.drugbank.com/drugs/DB01297ApprovedA beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Synonyms: N-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamideDeoxycholic acid
go.drugbank.com/drugs/DB03619ApprovedInvestigationalIn April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve aesthetic appearance and reduce facial fullness or convexity. … Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that
Thyroglobulin
go.drugbank.com/drugs/DB01584ApprovedWithdrawnThe active form of thyroxine, triiodothyronine, is produced both within the thyroid gland and periphery by 5'-deiodinase. … Patients with Hashimoto's thyroiditis or Graves' disease, frequently develop antibodies against thyroglobulin. Thyroglobulin is used to treat hypothyroidism.