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Bufexamac
go.drugbank.com/drugs/DB13346ApprovedWithdrawnBufexamac was also withdrawn by the EMA in April 2010. … It is typically administered topically for the treatment of subacute and chronic eczema of the skin, including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns,
Products: Norfemac Cream - 5%, Norfemac Ointment - 5%Mequinol
go.drugbank.com/drugs/DB09516ApprovedWithdrawnIt is used as an inhibitor for acrylic monomers and acrylonitirles, as a stabilizer for chlorinated hydrocarbons and ethyl cellulose, as an ultraviolet inhibitor, as a chemical intermediate in the manufacture … It is found as an active ingredient in topical drugs used for skin depigmentation indicated for the treatment of solar lentigines.
NCX 950
go.drugbank.com/drugs/DB05849ExperimentalNCX 950, beta2-adrenoceptor agonists is widely used in the treatment of pulmonary diseases.
Amylocaine
go.drugbank.com/drugs/DB09088ApprovedWithdrawnElsewhere in English speaking countries it was referred to as Stovaine, given the meaning of the French word 'fourneau' as 'stove' in English [L1882]. … Although amylocaine could be administered topically or injected, it was most widely used for spinal anesthesia [L1882].
Quazepam
go.drugbank.com/drugs/DB01589ApprovedIllicitIt was first approved in the US in 1985 and is used as a hypnotic for the treatment of insomnia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsRauwolfia serpentina root
go.drugbank.com/drugs/DB09363InvestigationalThe active ingredients in this drug are alkaloids and about 50 have been identified through various studies, although the primary psychoactive components appear to be reserpine, rescinnamine, and deserpidine … Reserpine is derived from Rauwolfia serpentina, and was commonly used as an antihypertensive agent in the 1950s [L1621]. Rauwolfia serpentina is also commonly referred to as _Sarpaghanda_ [A32097].
LYT-200
go.drugbank.com/drugs/DB18179InvestigationalLYT-200 is a fully human IgG4 monoclonal antibody directed against galectin-9.
AZD-9164
go.drugbank.com/drugs/DB12115InvestigationalAZD9164 has been used in trials studying the basic science and treatment of Chronic Obstructive Pulmonary Disease.
Categories: Receptor, Muscarinic M3, antagonists & inhibitorsSeladelpar
go.drugbank.com/drugs/DB12390ApprovedInvestigational[L51149] On August 14, 2024, seladelpar was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis,[L51154] which is a condition associated with aberrant bile acid metabolism
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesCardiolipin Biosynthesis CL(22:5(4Z,7Z,10Z,13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z))
smpdb.ca/view/SMP0029973MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...