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Displaying results 3471 - 3480 of 10000 in total
  1. Drug

    Canakinumab

    go.drugbank.com/drugs/DB06168
    ApprovedInvestigational

    both part of the Cryopyrin-Associated Periodic Syndromes (CAPS) as well as for patients 2 years of age and older to treat systemic juvenile idiopathic arthritis (SJIA). … Canakinumab is a recombinant, human anti-human-IL-1β monoclonal antibody that belongs to the IgG1/κ isotype subclass.

  2. Drug

    Sutimlimab

    go.drugbank.com/drugs/DB14996
    ApprovedInvestigational

    [A245154] Notably, none of these agents are approved for use in the treatment of CAD. … In addition to non-pharmacological strategies, such as counseling patients to keep warm and the use of red blood cell transfusions, approximately 70% of patients require pharmacological treatment.

    Synonyms: Humanized IgG4 monoclonal antibody against total complement component 1, subcomponent s
  3. Drug

    Olmesartan

    go.drugbank.com/drugs/DB00275
    ApprovedInvestigational

    [A185906,A185909,A185912] Orally available olmesartan is produced as the prodrug olmesartan medoxomil which is rapidly converted _in vivo_ to the pharmacologically active olmesartan. … Olmesartan is commonly used for the management of hypertension and Type 2 Diabetes-associated nephropathy, particularly in patients who are unable to tolerate ACE inhibitors.

  4. Drug

    Ensifentrine

    go.drugbank.com/drugs/DB16157
    ApprovedInvestigational

    Ensifentrine is a first-in-class, selective dual inhibitor of the phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) enzymes.

  5. Drug

    Evifacotrep

    go.drugbank.com/drugs/DB21510
    Investigational

    Evifacotrep is a small molecule drug. The usage of the INN stem '-cotrep' in the name indicates that Evifacotrep is a transient receptor potential canonical channel 5 (TRPC5) antagonist.

  6. Drug

    Carafiban

    go.drugbank.com/drugs/DB19813
    Experimental

    Carafiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Carafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).

  7. Drug

    Licostinel

    go.drugbank.com/drugs/DB19864
    Experimental

    Licostinel is a small molecule drug. The usage of the INN stem '-stinel' in the name indicates that Licostinel is a N-methyl-D-aspartate (NMDA) receptor co-agonist.

  8. Drug

    Orbofiban

    go.drugbank.com/drugs/DB20676
    Experimental

    Orbofiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Orbofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).

  9. Drug

    Gantofiban

    go.drugbank.com/drugs/DB20951
    Experimental

    Gantofiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Gantofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).

  10. Drug

    Roxifiban

    go.drugbank.com/drugs/DB21089
    Experimental

    Roxifiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Roxifiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).

    Categories: Platelet Glycoprotein GPIIb-IIIa Complex, antagonists & inhibitors