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Sphingolipid delta(4)-desaturase DES1
go.drugbank.com/bio_entities/BE0011584TargetHumansHas sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (PubMed:11937514, PubMed:30620337, PubMed:30620338). Catalyzes the equilibrium isomerization of retinols (By similar...
Synonyms: Cell migration-inducing gene 15 proteinSerine hydrolase RBBP9
go.drugbank.com/bio_entities/BE0011987TargetHumansSerine hydrolase (Probable) (PubMed:32196348). Catalyzes the hydrolytic activation of amino acid ester of the antiviral prodrug valacyclovir to its corresponding active drug, acyclovir (PubMed:32196348). May negatively regulate basal or ...
Synonyms: B5T-overexpressed gene proteinDexmecamylamine
go.drugbank.com/drugs/DB11807InvestigationalDexmecamylamine has been used in trials studying the basic science and treatment of Patients, Depression, Drug Abuse, Pharmacokinetics, and Renal Impairment, among others.
Ifetroban
go.drugbank.com/drugs/DB12321InvestigationalIfetroban has been used in trials studying the treatment of Skin Diseases, Autoimmune Diseases, Pathologic Processes, Scleroderma, Limited, and Scleroderma, Diffuse, among others.
Endostar
go.drugbank.com/drugs/DB11727InvestigationalEndostar has been investigated for the treatment of Non-small Cell Lung Cancer.
Depatuxizumab mafodotin
go.drugbank.com/drugs/DB11731InvestigationalDepatuxizumab/Denintuzumab mafodotin has been used in trials studying the treatment of Lymphoma, Gliosarcoma, Glioblastoma, Malignant Glioma, Squamous Cell Tumors, and Glioblastoma Multiforme.
Spebrutinib
go.drugbank.com/drugs/DB11764InvestigationalSpebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell.
TMC-647055
go.drugbank.com/drugs/DB11822InvestigationalTMC647055 has been used in trials studying the treatment of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, and Chronic Hepatitis C Virus.
JNJ-39393406
go.drugbank.com/drugs/DB11867InvestigationalJNJ-39393406 has been used in trials studying the treatment and basic science of DEPRESSION, Schizophrenia, Smoking Cessation, Cognition Disorders, and Alzheimer's Disease.
Luminespib
go.drugbank.com/drugs/DB11881InvestigationalAUY922 has been used in trials studying the treatment of Lymphoma, Breast Cancer, Metastatic Disease, Advanced Solid Tumors, and Hematologic Neoplasms, among others.