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Netarsudil
go.drugbank.com/drugs/DB13931ApprovedInvestigationalActing as both a rho kinase inhibitor and a norepinephrine transport inhibitor, Netarsudil is a novel glaucoma medication in that it specifically targets the conventional trabecular pathway of aqueous … A Rho kinase inhibitor with norepinephrine transport inhibitory activity that reduces production of aqueous As of December 18, 2017 the FDA approved Aerie Pharmaceutical's Rhopressa (netarsudil ophthalmic
Synonyms: (4-((1S)-1-(Aminomethyl)-2-(isoquinolin-6-ylamino)-2-oxoethyl)phenyl)methyl 2,4- dimethylbenzoateMineral oil
go.drugbank.com/drugs/DB11057ApprovedInvestigationalVet approvedMineral oil, or paraffin oil, is a mixture of higher alkanes from a mineral source, such as petroleum. … It is also used as a mild laxative for human or veterinary uses.
Mixtures: Major Prep Hemorrhoidal, Major Prep HemorrhoidalProducts: LAXAROL ORAL EMULSION 50% v/v, Mizon No.1 Kingsberry Cleansing Oi LDirucotide
go.drugbank.com/drugs/DB04921InvestigationalDeveloped at the University of Alberta, dirucotide is being investigated by BioMS Medical Corp. … Dirucotide is a synthetically prepared peptide. In particular, the sequence prepared is a 17 amino acid chain that is identical to a section of myelin basic protein (MBP) that is found in humans.
Rimegepant
go.drugbank.com/drugs/DB12457ApprovedInvestigational[L38814] The current standard of migraine therapy involves abortive treatment with "triptans", such as [sumatriptan], but these medications are contraindicated in patients with pre-existing cerebrovascular
Categories: MATE 1 Inhibitors, P-glycoprotein substratesGepirone
go.drugbank.com/drugs/DB12184ApprovedGepirone, an azapirone, is a pharmacologic analog of [buspirone] that acts selectively on the pre- and post-synaptic 5HT<sub>1A</sub> receptors. … It was not until an extended-release formulation of gepirone was made available that gepirone became a potential candidate for a new antidepressant.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingVosoritide
go.drugbank.com/drugs/DB11928ApprovedInvestigationalof a condition like achondroplasia. … of a peptidase-resistant formulation has allowed for its use as a viable treatment option in achondroplasia.
Categories: C-type Natriuretic Peptide AnalogGS030-DP
go.drugbank.com/drugs/DB17847InvestigationalIt is a component of GS030, an investigational optogenetic treatment, in combination with a medical device GS030-MD.[A259816, L46701] … It targets retinal ganglion cells that encodes a light-sensitive channelrhodopsin, ChrimsonR-tdTomato (ChR-tdT), delivered by an AAV2.7m8 vector.
LV-SMENP Vaccine
go.drugbank.com/drugs/DB15804ExperimentalLV-SMENP-DC is a vaccine candidate being developed by Shenzhen Geno-Immune Medical Institute that comprises dendritic cells that are modified with lentiviral vector-expressing synthetic minigene which … This vaccine is also administered with antigen-specific cytotoxic T lymphocytes (CTLs). As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.
Influenza B virus B/Washington/02/2019 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB15620ApprovedInvestigationalA seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.
Synonyms: Influenza B virus B/Washington/02/2019 antigen (formaldehyde inactivated)Mixtures: Influvac Tetra, suspension for injection in pre-filled syringe, Vaxigrip Tetra, Suspension for Injection in Pre-filled SyringeFormic acid
go.drugbank.com/drugs/DB01942ApprovedInvestigationalIt is commonly used as a preservative and antibacterial agent in livestock feed.
Mixtures: Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA, V-Natal