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Cyclosporine
go.drugbank.com/drugs/DB00091ApprovedInvestigationalVet approvedCyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. … [A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Categories: BSEP/ABCB11 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: Cyclosporin A, Cyclosporine AProgesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedPharmaceutical progesterone is made from a plant source as a starting material and is chemically identical to progesterone of human ovarian origin [FDA label]. … A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609].
Products: N/A, GESTAGENO®100MG CÁPSULAS DE GELATINA BLANDASecnidazole
go.drugbank.com/drugs/DB12834ApprovedInvestigational[A245503] Secnidazole has been available in many other countries in Europe, Asia, South America, and Africa for decades. … Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent.
Mixtures: GYNFLU® D TABLETAS, GYNFLU® D TABLETASProducts: DAKSOL TABLETAS DE 500 MG, SECNICHEN POLVO PARA RECONSTITUIR A SUSPENSIÓN ORALCinacalcet
go.drugbank.com/drugs/DB01012ApprovedInvestigationalCinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe.
Products: CINACALCET DR. REDDY'STeriflunomide
go.drugbank.com/drugs/DB08880ApprovedInvestigationalThe FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients using teriflunomide.
Products: TERIFLUNOMIDE DR. REDDY'S, Teriflunomid Genericon 14 mg FilmtablettenVerapamil
go.drugbank.com/drugs/DB00661ApprovedInvestigationalgreater potency than the R-enantiomer, but is metabolized at a higher rate. … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced
Products: Aa-verap, VERAPAMILO 240 MG TABLETAS DE LIBERACION MODIFICADAColistimethate
go.drugbank.com/drugs/DB01111ApprovedInvestigationalVet approvedColistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aer...
Products: COLISTIMETATO DE SODIO, COLISTIMETATO DE SODIO 2 MUIPyrithione
go.drugbank.com/drugs/DB06815ApprovedInvestigationalWhile its use has been approved in the early 1960's by the FDA [A32163], safety and effectiveness of pyrithione zinc has been reported for decades. … Pyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.
Mixtures: D-COL Personal Hygiene Convenience kitProducts: Life Brand Itchy Dry Scalp Anti-dandruff Shampoo, Dan-gardTetracycline
go.drugbank.com/drugs/DB00759ApprovedInvestigationalVet approvedWithdrawnThe FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria.
Products: TETRACICLINA DE 500 MG CAPSULAS, TETRACICLINA CAPSULAS DE 250 MGDonepezil
go.drugbank.com/drugs/DB00843ApprovedInvestigationalIn 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. … [L7916,L7937] A donepezil transdermal delivery system, Adlarity, was approved by the FDA in March 2022 for the treatment of Alzheimer's dementia.
Products: DONEPEZIL DR. REDDY'S, DOPECILO CLOHIDRATO DE DONEPECILO 10MG