Search

Displaying results 3571 - 3580 of 10000 in total
  1. Drug

    XK-469 free acid

    go.drugbank.com/drugs/DB19306
    Experimental

    Synonyms: PROPANOIC ACID, 2-(4-((7-CHLORO-2-QUINOXALINYL)OXY)PHENOXY)-, (±)-Categories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Raludotatug deruxtecan

    go.drugbank.com/drugs/DB19447
    Investigational

    Raludotatug deruxtecan is under investigation in clinical trial NCT06660654 (A Study of Raludotatug Deruxtecan in Participants With Advanced/metastatic Solid Tumors (Rejoice-pantumor01)).

    Synonyms: immunoglobulin G1-kappa, anti-[Homo sapiens CDH6(cadherin 6, K-cadherin (foetal kidney), cadherin 6 type 2)], humanized monoclonal antibody conjugated to deruxtecan, comprising a linker and a camptothecin, R-DXd
  3. Drug

    JNJ-1802

    go.drugbank.com/drugs/DB17734
    Experimental

    Synonyms: (+)-(2s)-2-(4-chloro-2-methoxyphenyl)-2-((3-methoxy-5-(methylsulfonyl)phenyl)amino)-1-(5-(trifluoromethoxy)-1h-indol-3-yl)ethanone, 2-(4-chloro-2-methoxyphenyl)-2-((3-methoxy-5-(methylsulfonyl)phenyl)amino)-1-(5-(trifluoromethoxy)-1h-indol-3-yl)ethanone, (s)-Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Elraglusib

    go.drugbank.com/drugs/DB16047
    Investigational

    Elraglusib is under investigation in clinical trial NCT04218071 (Actuate 1901: 9-ING-41 in Myelofibrosis).

    Synonyms: 1H-Pyrrole-2,5-dione, 3-(5-fluoro-3-benzofuranyl)-4-(5-methyl-5H-1,3-dioxolo(4,5-F)indol-7-yl)-, 3-(5-Fluoro-benzofuran-3-yl)-4-(5-methyl-5H-(1,3)dioxolo(4,5-F)indol-7-yl)-pyrrole-2,5-dione
  5. Drug

    SNS-314

    go.drugbank.com/drugs/DB06134
    Investigational

    SNS-314 inhibits tumor growth in a variety of preclinical models, and it is now being tested in single agent Phase 1 studies in patients with advanced solid tumours. … SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-(3-chlorophenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}urea
  6. Drug

    Monepantel

    go.drugbank.com/drugs/DB18755
    Investigational

    Synonyms: Benzamide, n-((1s)-1-cyano-2-(5-cyano-2-(trifluoromethyl)phenoxy)-1-methylethyl)-4-((trifluoromethyl)thio)-, N-(2-cyano-1-((2s)-5-cyano-2-(trifluoromethyl)phenoxy)propan-2-yl)-4-(trifluoromethylsulfanyl)benzamide
  7. Drug

    MePPEP C-11

    go.drugbank.com/drugs/DB19280
    Experimental

    Synonyms: (3r,5r)-5-(3-11c-methoxy-phenyl)-3-((r)-1-phenyl-ethylamino)-1-(4-trifluoromethyl-phenyl)-pyrrolidin-2-one, 2-pyrrolidinone, 5-(3-(methoxy-11c)phenyl)-3-(((1r)-1-phenylethyl)amino)-1-(4-(trifluoromethyl)phenyl)-, (3r,5r)-
  8. Drug

    Gunagratinib

    go.drugbank.com/drugs/DB18191
    Experimental

    Synonyms: (s)-1-(1-acryloylpyrrolidin-3-yl)-3-((3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1h-pyrazole-4-carboxamide, 1h-pyrazole-4-carboxamide, 3-(2-(3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1-((3s)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Ondansetron

    go.drugbank.com/drugs/DB00904
    ApprovedInvestigationalWithdrawn

    [L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation. … A competitive serotonin type 3 receptor antagonist.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: KEMOSET 4 MG FILM TABLET, 6 ADET, ZOFRAN 4 MG FILM TABLET, 6 ADET
  10. Drug

    Etizolam

    go.drugbank.com/drugs/DB09166
    Investigational

    Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. … It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: 4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine