Search

Displaying results 351 - 360 of 10000 in total
  1. Drug

    Axitinib

    go.drugbank.com/drugs/DB06626
    ApprovedInvestigational

    Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). … [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations.

    Synonyms: N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamideCategories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substrates with a Narrow Therapeutic Index
  2. Drug

    Baclofen

    go.drugbank.com/drugs/DB00181
    ApprovedInvestigational

    Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977.

    Mixtures: Innoprax-5Categories: GABA-B Receptor Agonists
  3. Drug

    Cysteine

    go.drugbank.com/drugs/DB00151
    ApprovedInvestigationalNutraceutical

    A thiol-containing non-essential amino acid that is oxidized to form cystine.

    Mixtures: NUMETA PED G 19 % E INFÜZYON IÇIN EMÜLSIYON, 1000 ML, Numeta G 13 % E Emulsion zur InfusionSynonyms: (2R)-2-amino-3-mercaptopropanoic acid, (R)-2-Amino-3-mercaptopropanoic acid
  4. Drug

    (2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid

    go.drugbank.com/drugs/DB08760
    Experimental

    Synonyms: (2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid
  5. Drug

    (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid

    go.drugbank.com/drugs/DB07842
    Experimental

    Synonyms: (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid
  6. Drug

    2-AMINO-4-CHLORO-3-HYDROXYBENZOIC ACID

    go.drugbank.com/drugs/DB04598
    Experimental

    Synonyms: 2-AMINO-4-CHLORO-3-HYDROXYBENZOIC ACID
  7. Drug

    Ataluren

    go.drugbank.com/drugs/DB05016
    ApprovedWithdrawn

    Ataluren is a novel, orally administered drug that targets nonsense mutations. … More specifically, ataluren is used in the small group of patients whose disease is caused by a specific genetic defect (called a ‘nonsense mutation’) in the dystrophin gene.

    Synonyms: 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acidCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Sulfinpyrazone

    go.drugbank.com/drugs/DB01138
    Approved

    A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesSynonyms: 1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl)pyrazolidine, 1,2-Diphenyl-4-(2'-phenylsulfinethyl)-3,5-pyrazolidinedione
  9. Drug

    {4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid

    go.drugbank.com/drugs/DB08078
    Experimental

    Synonyms: {4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid
  10. Drug

    2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine

    go.drugbank.com/drugs/DB07942
    Experimental

    Synonyms: 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine