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Carbocisteine
go.drugbank.com/drugs/DB04339ApprovedInvestigational[A230993] Carbocisteine is currently not FDA or Health Canada approved, but is approved for use in Asia, Europe, and South America. … [L32383] Several licenses for this drug were withdrawn following serious and fatal paradoxical effects after carbocisteine therapy in children; respiratory dress, dyspnea, and cough aggravation were
Doxepin
go.drugbank.com/drugs/DB01142ApprovedInvestigational[L5971] However, in 2010 it was approved for the treatment of insomnia. The latter indication was presented by Pernix Therapeutics.[L5974]
Categories: Antidepressive Agents Indicated for Depression, Adrenergic alpha-1 Receptor AntagonistsCollectin-12
go.drugbank.com/bio_entities/BE0015432TargetHumansScavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast.
Synonyms: Nurse cell scavenger receptor 2, Scavenger receptor class A member 4Etomidate
go.drugbank.com/drugs/DB00292ApprovedInvestigationalImidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Categories: Adrenergic alpha-2 Receptor AgonistsBinimetinib
go.drugbank.com/drugs/DB11967ApprovedInvestigational[A34275,L3335] On June 27, 2018, the Food and Drug Administration approved the combination of [Encorafenib] and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients
Atractylodes japonica root oil
go.drugbank.com/drugs/DB11270ApprovedWithdrawnIt is present in some cosmetic products such as whitening creams as an active ingredient and lubricant for skin irritation.
Mafenide
go.drugbank.com/drugs/DB06795ApprovedVet approvedWithdrawnIn November 2022, the use of mafenide acetate (powder for 5% topical solution) was withdrawn by the FDA due to an unresolved confirmatory study required to fulfill the accelerated approval requirements
Contusugene ladenovec
go.drugbank.com/drugs/DB05322InvestigationalAdvexin is a well-tolerated and efficacious treatment for numerous cancers, both as monotherapy and in combination with radiation and/or chemotherapy agents.
Phenolsulfonphthalein
go.drugbank.com/drugs/DB13212ExperimentalPhenolsulfonphthalein is being investigated for use clinically due to its weak estrogen mimicking actions [A174964].
Categories: Tests for Renal Function and Ureteral InjuriesTerconazole
go.drugbank.com/drugs/DB00251Approved[A178093]Due to the existence of 2 stereocentres, there are 4 possible stereoisomers for terconazole.