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DNB-001
go.drugbank.com/drugs/DB05757InvestigationalIn preclinical animal models, DNB-001 has demonstrated potent IOP- lowering effects as well as neuroprotective effects on the optic nerve. … DNB-001 is a first-in-class oral therapy with dual mechanism of action, which is initially being developed for the treatment of glaucoma.
DG041
go.drugbank.com/drugs/DB05027ExperimentalDG041, an anti-platelet compound, has shown to be a selective and potent antagonist of the EP3 receptor for prostaglandins E2. … EP3 is a target that associates with increased risk of various vascular diseases.
NKX101
go.drugbank.com/drugs/DB18131InvestigationalNKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.
Synonyms: a fourth generation activating chimeric receptor (ACR) natural killer (NK) cell therapy engineered with an NKG2D ACR, OX40 costimulatory domain, CD3zeta signaling moiety, and membrane bound IL-15 (mb-IL15rAAV1-CB-hAAT
go.drugbank.com/drugs/DB18724InvestigationalrAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector.
Synonyms: rAAV1-CB-hAATABG-023
go.drugbank.com/drugs/DB18829ExperimentalABG-023 is a glucagon analog which is soluble and solution-stable.[L50778]
NS-3728
go.drugbank.com/drugs/DB05835ExperimentalNS3728 is an orally active chloride channel blocker for the treatment of cancer.
AP-101
go.drugbank.com/drugs/DB17947InvestigationalAP-101 is a recombinant human antibody directed against human misfolded superoxide dismutase 1.
Satricabtagene autoleucel
go.drugbank.com/drugs/DB18288InvestigationalSatricabtagene autoleucel is an autologous CAR T-cell product candidate against protein Claudin18.2 (CLDN18.2).
Audencel
go.drugbank.com/drugs/DB18386InvestigationalAV-0113 consists of IL-12 secreting dendritic cells loaded with autologous tumor lysate.