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Zebularine
go.drugbank.com/drugs/DB03068ExperimentalA chemically stable, cytidine analog that displays anti-tumor properties. It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates. … Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo.
Synonyms: 1-beta-D-ribofuranosyl-2(1H)-pyrimidinone, 1-beta-D-ribofuranosylpyrimidin-2(1H)-oneCategories: Heterocyclic Compounds, 1-RingTreprostinil
go.drugbank.com/drugs/DB00374ApprovedInvestigationalHowever, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room temperature. … [L41855,L41860] The first agent approved for the treatment of PAH was [epoprostenol], a synthetic prostacyclin that significantly increases patients' quality of life.
Categories: Prostaglandins I, Cytochrome P-450 SubstratesProducts: TREPROSTINIL DR. REDDY'S, REMODULIN 5 mg/ml InfusionslösungMevonlerbart
go.drugbank.com/drugs/DB19416InvestigationalMevonlerbart is under investigation in clinical trial NCT06602726 (A Study to Demonstrate How Well REGN1908-1909 Works in Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Cat Allergy
Synonyms: Anti-cat allergen fel d 1 monoclonal anitbody regn-1909, immunoglobulin G4-kappa, anti-[Fel d 1 (Felis silvestris catus (domestic cat) allergen 1)], Homo sapiens monoclonal antibodyUdifitimod
go.drugbank.com/drugs/DB19053InvestigationalUdifitimod is under investigation in clinical trial NCT05014438 (A Study of BMS-986166 or Branebrutinib for the Treatment of Participants With Atopic Dermatitis).
Synonyms: ((1R,3S)-1-amino-3-((S)-6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol, [(1R,3S)-1-amino-3-{(6S)-6-[2-(2-methoxyphenyl)ethyl]- 5,6,7,8-tetrahydronaphthalen-2-yl}cyclopentyl]methanolMMDA
go.drugbank.com/drugs/DB01442ExperimentalIllicitMMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. … MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg.
Synonyms: 5-Methoxy-3,4-methylenedioxyamphetamine, 3-methoxy-methylenedioxyamphetamineCategories: Serotonin 5-HT2 Receptor Agonists, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesIfinatamab deruxtecan
go.drugbank.com/drugs/DB18212InvestigationalSynonyms: -CHAIN, DIMER, THIOETHER WITH N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOH, IMMUNOGLOBULIN G1, ANTI-(HUMAN B7 HOMOLOG 3 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .KAPPA.Autologous ex vivo expanded cd4+-enriched leukocytes treated with the de-methylating agent 5-aza-deoxycytidine
go.drugbank.com/drugs/DB19219InvestigationalSynonyms: Autologous ex vivo expanded cd4+-enriched leukocytes treated with the de-methylating agent 5-aza-deoxycytidineAgmatine
go.drugbank.com/drugs/DB08838ExperimentalAs an investigational drug, it is being studied in a non-blinded prospective case study in the United States looking at patients who have been diagnosed with small fiber peripheral neuropathy between the … Agmantine is a natural metabolite of the amino acid arginine.
Synonyms: 1-amino-4-guanidobutane, N-(4-aminobutyl)guanidineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE
go.drugbank.com/drugs/DB08164ExperimentalSynonyms: (3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINEN-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE
go.drugbank.com/drugs/DB08270ExperimentalSynonyms: N-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE