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Cycrimine
go.drugbank.com/drugs/DB00942ApprovedCycrimine is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and management of Parkinson's disease.
Miocamycin
go.drugbank.com/drugs/DB13287ApprovedThis drug may be marketed in Japan for clinical use as it is listed in the Japanese pharmacopeia [L5737]. … or as an alternative to erythromycin treatment [A176170].
Tedizolid
go.drugbank.com/drugs/DB14569ApprovedInvestigationalThis product is currently available as both an oral tablet and as a powder for intravenous injection.[L11232] … [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate (SIVEXTRO®).
Ximelagatran
go.drugbank.com/drugs/DB04898ApprovedWithdrawnIn 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries … Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former.
Synonyms: ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin-1-yl]- 2-oxo-ethyl]amino]acetateBird pepper
go.drugbank.com/drugs/DB14262ApprovedBird pepper is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Rice bran
go.drugbank.com/drugs/DB14361ApprovedRice bran is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Milk thistle
go.drugbank.com/drugs/DB14375ApprovedInvestigationalMilk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Pexidartinib
go.drugbank.com/drugs/DB12978ApprovedInvestigationalIn clinical trials, pexidartinib was shown to promote improvements in patient symptoms and functional outcomes in TGCT. … [A182243] Pexidartinib is available in oral formulations and it is commonly marketed as Turalio.[L7901]
XL999
go.drugbank.com/drugs/DB05014InvestigationalXL999 induces a cell-cycle block by a mechanism distinct from those previously identified and exhibits broad antitumor activity in xenograft models. … XL999 has the potential to prevent tumor growth — both directly by a novel effect on tumor cell proliferation and indirectly through inhibition of the host angiogenic response.
Pazopanib
go.drugbank.com/drugs/DB06589ApprovedInvestigationalIt is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.