This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Milk thistle
- DrugBank Accession Number
- DB14375
- Background
Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
- Type
- Biotech
- Groups
- Approved, Experimental, Investigational
- Synonyms
- 822i9lej7s
- Cardui Mariae Fructus
- Carduus Marianus
- Carduus Marianus Preparation
- Carduus Marianus Seed
- Fruit of Silybum Marianum
- Holy Thistle Seed
- Lady's Thistle Seed
- Mariana Mariana Seed
- Mary's Thistle Seed
- Milk Thistle Extract
- Milk Thistle Fruit
- Milk Thistle Seed
- Milk Thistle Seed Extract
- Milk Thistle Silymarin
- Milkthistle Fruit (Silybum Marianum L. Gaertner)
- Saint Mary's Thistle Extract
- Shuifeiji
- Silybi Fructus
- Silybi Mariani Fructus (Silybum Marianum L. Gaertner)
- Silybum Marianum Dry Fruit
- Silybum Marianum Dry Fruit Extract
- Silybum Marianum Extract
- Silybum Marianum Fruit
- Silybum Marianum Fruit Extract
- Silybum Marianum Seed
- Silybum Marianum Seed Extract
Pharmacology
- Indication
Not Available
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Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Dr. Super Khan Capsule 260 mg/1 Oral HLscience Co Ltd 2013-07-05 2018-02-12 US 
Enrich's Life Path L.P. Formula Capsule 12000 mg / 8 cap Oral Enrich International 1999-10-15 2001-09-28 Canada 
Ethical Herbals Milk Thistle Extract Tablet 175 mg / tab Oral Ashbury Research Corporation Not applicable Not applicable Canada Milk Thistle Capsule 150 mg Oral Holista Health (Canada) Inc. 1996-12-31 2008-07-17 Canada Milk Thistle - Liq Liquid 2 g / mL Oral Sisu Inc. 1995-12-31 2004-09-01 Canada Milk Thistle Ext. Tablets Tablet 70 mg Oral Metagenics, Inc. 1999-01-22 2006-08-14 Canada Relive Capsule 150 mg / cap Oral Holista Health (Canada) Inc. 1997-06-01 2001-08-01 Canada - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image EUGICA FORT Milk thistle (0.36 mg) + Cajuput oil (50 mg) + Eucalyptol (100 mg) + Ginger oil (0.75 mg) + Levomenthol (0.5 mg) + Soybean oil (50 mg) Capsule บริษัท เมก้า ไลฟ์ไซแอ็นซ์ จำกัด (มหาชน) 2019-05-27 Not applicable Thailand 
HEPROTEC Milk thistle (200 mg) + Cyanocobalamin (2.4 mcg) + Nicotinamide (24 mg) + Calcium pantothenate (16 mg) + Pyridoxine hydrochloride (8 mg) + Riboflavin (8 mg) + Thiamine mononitrate (8 mg) Capsule บริษัท พาตาร์แลบ (2517) จำกัด จำกัด 2013-03-19 2019-10-21 Thailand Milk Thistle Plus Turmeric Milk thistle (5.6 g / cap) + Turmeric (150 mg / cap) Capsule Oral Puresource Inc. Not applicable Not applicable Canada - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Dr. Super Khan Milk thistle (260 mg/1) Capsule Oral HLscience Co Ltd 2013-07-05 2018-02-12 US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- U946SH95EE
- CAS number
- 65666-07-1
References
- General References
- Not Available
- External Links
- 350520
- Wikipedia
- Silybum_marianum
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Completed Basic Science Prostate Cancer 1 2 Completed Prevention Chronic Hepatitis C Virus (HCV) Infection 1 2 Completed Prevention End Stage Renal Disease (ESRD) / Hemodialysis Treatment 1 2 Completed Treatment Chronic Hepatitis C Virus (HCV) Infection 1 2 Completed Treatment Diabetic Nephropathy 1 2 Completed Treatment Gambling Disorder / Pathological Gambling Disorder 1 2 Completed Treatment Hair Pulling Disorder / Trichotillomania 1 2 Completed Treatment Non Alcoholic Steatohepatitis (NASH) 1 2 Terminated Treatment Dyslipidemia / Menopause / Obesity 1 2 Withdrawn Treatment Body Dysmorphic Disorders 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Capsule Oral 260 mg/1 Capsule Oral 12000 mg / 8 cap Tablet Oral 175 mg / tab Tablet Oral 7.5 g / tab Capsule Capsule Oral 150 mg Liquid Oral 2 g / mL Tablet Oral 70 mg Capsule Oral Capsule Oral 150 mg / cap - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at July 05, 2018 17:14 / Updated at December 03, 2023 06:21