Milk thistle

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Milk thistle
DrugBank Accession Number
DB14375
Background

Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Type
Biotech
Groups
Approved, Experimental, Investigational
Synonyms
  • 822i9lej7s
  • Cardui Mariae Fructus
  • Carduus Marianus
  • Carduus Marianus Preparation
  • Carduus Marianus Seed
  • Fruit of Silybum Marianum
  • Holy Thistle Seed
  • Lady's Thistle Seed
  • Mariana Mariana Seed
  • Mary's Thistle Seed
  • Milk Thistle Extract
  • Milk Thistle Fruit
  • Milk Thistle Seed
  • Milk Thistle Seed Extract
  • Milk Thistle Silymarin
  • Milkthistle Fruit (Silybum Marianum L. Gaertner)
  • Saint Mary's Thistle Extract
  • Shuifeiji
  • Silybi Fructus
  • Silybi Mariani Fructus (Silybum Marianum L. Gaertner)
  • Silybum Marianum Dry Fruit
  • Silybum Marianum Dry Fruit Extract
  • Silybum Marianum Extract
  • Silybum Marianum Fruit
  • Silybum Marianum Fruit Extract
  • Silybum Marianum Seed
  • Silybum Marianum Seed Extract

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products
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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Dr. Super KhanCapsule260 mg/1OralHLscience Co Ltd2013-07-052018-02-12US flag
Enrich's Life Path L.P. FormulaCapsule12000 mg / 8 capOralEnrich International1999-10-152001-09-28Canada flag
Ethical Herbals Milk Thistle ExtractTablet175 mg / tabOralAshbury Research CorporationNot applicableNot applicableCanada flag
Milk ThistleCapsule150 mgOralHolista Health (Canada) Inc.1996-12-312008-07-17Canada flag
Milk Thistle - LiqLiquid2 g / mLOralSisu Inc.1995-12-312004-09-01Canada flag
Milk Thistle Ext. TabletsTablet70 mgOralMetagenics, Inc.1999-01-222006-08-14Canada flag
ReliveCapsule150 mg / capOralHolista Health (Canada) Inc.1997-06-012001-08-01Canada flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
EUGICA FORTMilk thistle (0.36 mg) + Cajuput oil (50 mg) + Eucalyptol (100 mg) + Ginger oil (0.75 mg) + Levomenthol (0.5 mg) + Soybean oil (50 mg)Capsuleบริษัท เมก้า ไลฟ์ไซแอ็นซ์ จำกัด (มหาชน)2019-05-27Not applicableThailand flag
HEPROTECMilk thistle (200 mg) + Cyanocobalamin (2.4 mcg) + Nicotinamide (24 mg) + Calcium pantothenate (16 mg) + Pyridoxine hydrochloride (8 mg) + Riboflavin (8 mg) + Thiamine mononitrate (8 mg)Capsuleบริษัท พาตาร์แลบ (2517) จำกัด จำกัด2013-03-192019-10-21Thailand flag
Milk Thistle Plus TurmericMilk thistle (5.6 g / cap) + Turmeric (150 mg / cap)CapsuleOralPuresource Inc.Not applicableNot applicableCanada flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Dr. Super KhanMilk thistle (260 mg/1)CapsuleOralHLscience Co Ltd2013-07-052018-02-12US flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
U946SH95EE
CAS number
65666-07-1

References

General References
Not Available
RxNav
350520
Wikipedia
Silybum_marianum
AHFS Codes
  • 92:01.00* — Herbs and Natural Products

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedBasic ScienceProstate Cancer1
2CompletedPreventionChronic Hepatitis C Virus (HCV) Infection1
2CompletedPreventionEnd Stage Renal Disease (ESRD) / Hemodialysis Treatment1
2CompletedTreatmentChronic Hepatitis C Virus (HCV) Infection1
2CompletedTreatmentDiabetic Nephropathy1
2CompletedTreatmentHair Pulling Disorder / Trichotillomania1
2CompletedTreatmentNon-Alcoholic Steatohepatitis1
2RecruitingTreatmentBody Dysmorphic Disorders1
2RecruitingTreatmentGambling Disorder / Pathological Gambling1
2TerminatedTreatmentBMI >30 kg/m2 / Dyslipidemia / Menopause1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
CapsuleOral260 mg/1
CapsuleOral12000 mg / 8 cap
TabletOral175 mg / tab
TabletOral7.5 g / tab
Capsule
CapsuleOral150 mg
LiquidOral2 g / mL
TabletOral70 mg
CapsuleOral
CapsuleOral150 mg / cap
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on July 05, 2018 17:14 / Updated on June 22, 2021 09:25