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Displaying results 3651 - 3660 of 10000 in total
  1. Drug

    AMG-553

    go.drugbank.com/drugs/DB18346
    Investigational

    AMG-553 is an adoptive, anti-FLT3 chimeric antigen receptor T-cell therapy generated through transduction of autologous T-cells with a self-inactivating human immunodeficiency virus-1 based lentiviral

  2. Drug

    Glenvastatin

    go.drugbank.com/drugs/DB21374
    Experimental

    The usage of the INN stem '-vastatin' in the name indicates that Glenvastatin is a antihyperlipidaemic substance, HMG COA reductase inhibitor.

  3. Drug

    BMS-214662

    go.drugbank.com/drugs/DB12234
    Investigational

    treatment of Childhood Myelodysplastic Syndromes, Refractory Anemia With Excess Blasts, Recurrent Adult Acute Myeloid Leukemia, Relapsing Chronic Myelogenous Leukemia, and Adult Acute Promyelocytic Leukemia (M3

  4. Drug

    Bepotastine

    go.drugbank.com/drugs/DB04890
    Approved

    Bepotastine was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus in July 2000 and January 2002, respectively, and is marketed by Tanabe Seiyaku Co., Ltd. under the

  5. Drug

    Difamilast

    go.drugbank.com/drugs/DB14987
    ApprovedInvestigational

    Atopic dermatitis is a chronic and fluctuating pruritic inflammatory skin condition characterized by pruritic eczema and is also marked by exacerbations and remissions. … The drug is indicated for the topical treatment of mild to moderate atopic dermatitis in adults and pediatric patients 2 years of age and older [L55042]. It is approved in Japan and the United States.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inducers
  6. Drug

    Phentolamine

    go.drugbank.com/drugs/DB00692
    ApprovedInvestigational

    While initially introduced to the market for the treatment of hypertension, this clinical use was halted due to cardiovascular and gastrointestinal adverse effects with the prolonged use of large oral

    Synonyms: 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazolineProducts: Rogitine 5mg/vial
  7. Drug

    Asparagine

    go.drugbank.com/drugs/DB00174
    ApprovedNutraceuticalWithdrawn

    It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)

    Mixtures: AMINOPLASMAL-10% E INFUSION, AMINOPLASMAL HEPA 10%-500ML GLASS BOTTLE
  8. Drug

    Durlobactam

    go.drugbank.com/drugs/DB16704
    ApprovedInvestigational

    It is typically given in combination with [sulbactam] to protect it from degradation by certain serine-beta-lactamases. … [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP), caused by susceptible isolates of _Acinetobacter baumannii-calcoaceticus_

    Synonyms: (2S,5R)-2-CARBAMOYL-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL SULFATE, SULFURIC ACID, MONO((2S,5R)-2-(AMINOCARBONYL)-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL) ESTER
  9. Drug

    COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection

    go.drugbank.com/drugs/DB16520
    Experimental

    Presentation Therapeutic Biologics (COVID-19--AP) (AP-TP-Bio))[L31333]. … COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection is an intradermal injection currently being investigated in the clinical trial NCT03348670 (Discovery Stage (Proof-of-concept) COVID-19 Antigen

    Synonyms: COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection, COVID-19 Therapeutic Biologics - Spike-GM-CSF Protein Lactated Ringer's Injection
  10. Drug

    Atrasentan

    go.drugbank.com/drugs/DB06199
    ApprovedInvestigational

    to be approved for this condition. … [L52855] In April 2025, atrasentan was granted accelerated approval by the FDA for the reduction of proteinuria in patients with primary IgA nephropathy, becoming the first endothelin A receptor antagonist

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP2B6 Inhibitors