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Displaying results 3661 - 3670 of 10000 in total
  1. Drug

    AZD-7268

    go.drugbank.com/drugs/DB19203
    Investigational

    AZD-7268 is under investigation in clinical trial NCT01020799 (AZD7268 Safety and Tolerability Study).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: Benzamide, n-(2-hydroxyethyl)-n-methyl-4-(8-quinolinyl(1-(4-thiazolylmethyl)-4-piperidinylidene)methyl)-, N-(2-hydroxyethyl)-n-methyl-4-(8-quinolinyl(1-(4-thiazolylmethyl)-4-piperidinylidene)methyl)-benzamide
  2. Drug

    AZD-2836

    go.drugbank.com/drugs/DB06031
    Investigational

    AZD-2836 is an inhibitor of the nonstructural protein 5A (NS5A).[A264853] The drug is being investigated for treatment of hepatitis C because AZD-2836 has in vitro anti-HCV activity.[A264858]

    Synonyms: 6-(3,4-Dimethoxyphenyl)-N-[4-(1H-1,2,4-triazol-1-yl)phenyl]-4-quinazolinamine
  3. Drug

    Tetramethylpyrazine nitrone

    go.drugbank.com/drugs/DB23609
    Investigational

    Synonyms: (Z)-N-TERT-BUTYL-1-(3,5,6-TRIMETHYLPYRAZIN-2-YL)METHANIMINE OXIDE, N-TERT-BUTYL-1-(3,5,6-TRIMETHYLPYRAZIN-2-YL)METHANIMINE OXIDECategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Flumazenil

    go.drugbank.com/drugs/DB01205
    ApprovedInvestigational

    Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine … receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingProducts: ANEXATE 1 MG/10 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADET, ANEXATE 0,5 MG/5 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADET
  5. Drug

    Agmatine

    go.drugbank.com/drugs/DB08838
    Experimental

    As an investigational drug, it is being studied in a non-blinded prospective case study in the United States looking at patients who have been diagnosed with small fiber peripheral neuropathy between the … Agmantine is a natural metabolite of the amino acid arginine.

    Synonyms: 1-amino-4-guanidobutane, N-(4-aminobutyl)guanidineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  6. Drug

    Somatotropin

    go.drugbank.com/drugs/DB00052
    ApprovedInvestigational

    [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid residues with a molecular weight of 22 kDa. … [A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults under a wide variety of brand names.

    Mixtures: Nutropin - Kit Pws(5mg) & Liq(10ml) Im ScCategories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 Inducers
  7. Drug

    Mezagitamab

    go.drugbank.com/drugs/DB16370
    Investigational

    Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and Efficacy of TAK-079 in Participants With Persistent/chronic Primary Immune Thrombocytopenia

    Synonyms: (1-453) (HOMO SAPIENS VH (IGHV3-23*01 (89%) (IGHD)-I, IMMUNOGLOBULIN G1-LAMBDA, ANTI-(HOMO SAPIENS ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 1 (2'-PHOSPHO-ADP-RIBOSYL CYCLASE, ANTIGENE CD38))HUMANIZED MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN HUMANIZED
  8. Drug

    CPG-52852

    go.drugbank.com/drugs/DB12476
    Investigational

    852A has been used in trials studying the treatment of Melanoma, Neoplasms, Breast Cancer, Ovarian Cancer, and Cervical Cancer, among others.

    Synonyms: N-[4-(4-amino-2-ethylimidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide
  9. Drug

    S-40503

    go.drugbank.com/drugs/DB13938
    Experimental

    S-40503 is an investigational selective androgen receptor modulator (SARM) developed for the treatment of osteoporosis by the Japanese company Kaken Pharmaceuticals.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-(4-(Dimethylamino)-6-nitro-1,2,3,4-tetrahydroquinolin-2-yl)-2-methylpropan-1-ol
  10. Drug

    Pixofisiran

    go.drugbank.com/drugs/DB17294
    Experimental

    Synonyms: Rna, (a-g-a-a-g-u-u-g-g-c-a-u-g-g-u-a-g-c-c-c-u-u-g-g-g), complex with rna (c-c-c-a-a-g-g-g-c-u-a-c-c-a-u-g-c-c-a-a-c-u-u-c-u) (1:1), Cotsiranib tgf-.beta.1 si-rna free acid component