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ICA-105665
go.drugbank.com/drugs/DB06089InvestigationalIt is a novel opener of the KCNQ ion channel which in preclinical studies has demonstrated a broad spectrum of activity in models of epilepsy. … In addition, ICA-105665 has also demonstrated activity in certain models of neuropathic pain.
Neovastat
go.drugbank.com/drugs/DB05387InvestigationalIt is currently in international Phase III trials for renal cell carcinoma and non-small-cell lung cancer. … Neovastat is a naturally occurring anti-angiogenic compound, extracted from cartilage, with multiple anti-angiogenic mechanisms of action that provide broad therapeutic potential for a number of diseases
Isosorbide
go.drugbank.com/drugs/DB09401ApprovedInvestigationalIsosorbide was previously available in an oral formulation for the reduction of intraocular pressure. It was approved by the FDA in 1980, but has since been discontinued. … Currently, isosorbide is an organic nitrate currently available in the [isosorbide mononitrate] and [isosorbide dinitrate] forms, and is used for the prevention of angina.
Rumex acetosella whole
go.drugbank.com/drugs/DB14166ApprovedWithdrawnRumex acetosella whole allergenic extract is used in allergenic testing.
Rumex crispus top
go.drugbank.com/drugs/DB14167ApprovedWithdrawnRumex crispus top allergenic extract is used in allergenic testing.
Salix nigra bark
go.drugbank.com/drugs/DB14169ApprovedWithdrawnSalix nigra bark allergenic extract is used in allergenic testing.
Asimadoline
go.drugbank.com/drugs/DB05104InvestigationalIt has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients and has the potential for treating other gastrointestinal diseases. … Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist.
Butobarbital
go.drugbank.com/drugs/DB01353ApprovedIllicitButobarbital is a sedative and a hypnotic drug.
Sulfaphenazole
go.drugbank.com/drugs/DB06729ApprovedSulfaphenazole is a sulfonamide antibacterial.
Synonyms: N'-(1-phenylpyrazol-5-yl)sulfanilamide, N(1)-(1-phenylpyrazol-5-yl)sulfanilamideEllagic acid
go.drugbank.com/drugs/DB08846InvestigationalIn pomegranates, there are several therapeutic compounds but ellagic acid is the most active and abundant. Ellagic acid is also present in vegetables. … Ellagic acid is present in several fruits such as cranberries, strawberries, raspberries, and pomegranates.