DB06729ApprovedSmall molecule
Sulfaphenazole is a sulfonamide antibacterial.
- Mechanism
- Curator reviewed
Sulfaphenazole is a sulfonamide antibacterial. In bacteria, antibacterial sulfonamides act as competitive inhibitors of the enzyme dihydropteroate synthetase (DHPS), an enzyme involved in folate synthesis. As such, the microorganism will be "starved" of folate and die.
- Primary indication
- For the treatment bacterial infections.Curator reviewed
- Formula / weight
- C15H14N4O2S · 314.362 g/mol (avg)
- Also known as
- Sulphaphenazole
Resolves to
Clinical / RWD
Structure
InChIKey
QWCJHSGMANYXCW-UHFFFAOYSA-NSMILESNC1=CC=C(C=C1)S(=O)(=O)NC1=CC=NN1C1=CC=CC=C1Targets
What you can answer from here — as of January 29, 2025
2Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Sulfaphenazole, and which of those have an active Phase 3 trial?
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