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Displaying results 3711 - 3720 of 8196 in total
  1. Drug

    Levamlodipine

    go.drugbank.com/drugs/DB09237
    ApprovedInvestigational

    Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of [amlodipine], an antihypertensive medication.

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  2. Drug

    Aprepitant

    go.drugbank.com/drugs/DB00673
    ApprovedInvestigational

    Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting … Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Inducers
  3. Drug

    Sulfaquinoxaline

    go.drugbank.com/drugs/DB11464
    ExperimentalVet approved

    Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K as

  4. Drug

    Dofequidar

    go.drugbank.com/drugs/DB14067
    Investigational

    Dofequidar is an antineoplastic agent.

    Categories: P-glycoprotein inhibitors
  5. Drug

    Cambritaxestat

    go.drugbank.com/drugs/DB18723
    Investigational

    Cambritaxestat is an autotaxin inhibitor.

  6. Drug

    Excindogen

    go.drugbank.com/drugs/DB18754
    Experimental

    Excindogen is an investigational immunotherapy.

  7. Drug

    Pirodavir

    go.drugbank.com/drugs/DB08012
    Experimental

    Pirodavir is an antipicornavirus agent.

  8. Drug

    Asfotase alfa

    go.drugbank.com/drugs/DB09105
    ApprovedInvestigational

    Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP). Hypophosphatasia is almost always fatal when severe skele...

  9. Drug

    Deoxycholic acid

    go.drugbank.com/drugs/DB03619
    ApprovedInvestigational

    Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that tissue. In April 2015, deoxycholi...

  10. Drug

    Avutometinib

    go.drugbank.com/drugs/DB15254
    ApprovedInvestigational

    Avutometinib is a small molecule kinase inhibitor targeted against RAF/MEK1, key regulators of the RAS/RAF/MEK/ERK (MAPK) pathway. The MAPK pathway is implicated in variety of cancers, playing a key role in tumor cell proliferation, diff...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates