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Displaying results 3711 - 3720 of 3730 in total
  1. Drug

    Substance P

    go.drugbank.com/drugs/DB19198
    Investigational

    Substance P is under investigation in clinical trial NCT03738878 (Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1).

    Synonyms: Substance P, Neurokinin pCategories: Substance P, antagonists & inhibitors
  2. Drug

    Florquinitau (18F)

    go.drugbank.com/drugs/DB19215
    Approved

    Florquinitau F 18 is a radioactive diagnostic drug used as a fluorine-18–labeled positron emission tomography (PET) tracer. It binds to aggregated tau protein, which in Alzheimer's disease forms the neurofibrillary tangles (NFTs) that ar...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  3. Drug

    Camizestrant

    go.drugbank.com/drugs/DB19218
    ApprovedInvestigational

    Camizestrant is an oral selective estrogen receptor degrader (SERD) and estrogen receptor (ER) antagonist used in combination with a CDK4/6 inhibitor to treat hormone receptor-positive, HER2-negative locally … [L64094,L64107] It binds the ligand binding domain of ERα, antagonizing ERα encoded by both wild-type and mutated *ESR1* and inducing proteasome-dependent degradation of the receptor without agonizing

    Categories: Estrogen Receptor Antagonists, Selective Estrogen Receptor Degraders
  4. Drug

    Hydrastinine

    go.drugbank.com/drugs/DB19359
    Experimental

    Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  5. Drug

    Sorbitan monolaurate

    go.drugbank.com/drugs/DB20157
    Investigational

    Sorbitan monolaurate is a small molecule drug. Sorbitan monolaurate has a monoisotopic molecular weight of 346.24 Da.

    Categories: P-glycoprotein inhibitors
  6. Drug

    Enerisant

    go.drugbank.com/drugs/DB20605
    Experimental

    The usage of the INN stem '-isant' in the name indicates that Enerisant is a histamine H3​ receptor antagonist. Enerisant has a monoisotopic molecular weight of 398.23 Da.

    Categories: P-glycoprotein substrates
  7. Drug

    Fluroxene

    go.drugbank.com/drugs/DB20681
    Experimental

    Fluroxene is a small molecule drug. Fluroxene has a monoisotopic molecular weight of 126.03 Da.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  8. Drug

    Telmapitant

    go.drugbank.com/drugs/DB20768
    Experimental

    The usage of the INN stem '-pitant' in the name indicates that Telmapitant is a neurokinin NK1​ (substance P) receptor antagonist. Telmapitant has a monoisotopic molecular weight of 515.16 Da.

  9. Drug

    Taltobulin

    go.drugbank.com/drugs/DB20832
    Experimental

    Taltobulin is a small molecule drug. Taltobulin has a monoisotopic molecular weight of 473.33 Da.

    Categories: P-glycoprotein substrates
  10. Drug

    Tabimorelin

    go.drugbank.com/drugs/DB20892
    Experimental

    Tabimorelin is a small molecule drug. The usage of the INN stem '-relin' in the name indicates that Tabimorelin is a pituitary hormone-release stimulating peptide. Tabimorelin has a monoisotopic molecular weight of 528.31 Da.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors