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Rozanolixizumab
go.drugbank.com/drugs/DB14919ApprovedInvestigationalRozanolixizumab-noli is available under the brand name RYSTIGGO and was developed by UCB. … [L47122] Rozanolixizumab was also approved by the European Commission on January 5, 2024.[L50973]
Isradipine
go.drugbank.com/drugs/DB00270ApprovedIsradipine belongs to the dihydropyridine (DHP) class of calcium channel blockers (CCBs), the most widely used class of CCBs. It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blo...
Oxyphenisatin acetate
go.drugbank.com/drugs/DB14627ApprovedWithdrawnOxyphenisatin acetate is the pro-drug of [oxyphenisatin] (3,3-bis(4-hydroxyphenyl)-1H-indol-2-one). The FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.[L43942]
Avacincaptad pegol
go.drugbank.com/drugs/DB15165ApprovedInvestigationalIt was developed to treat an advanced form of age-related macular degeneration (AMD) called geographic atrophy (GA). … [A260801] Although anti-VEGF therapy is available for the neovascular form of AMD, no treatment was approved for GA.
Phenaridine
go.drugbank.com/drugs/DB09178ExperimentalIllicitIt was developed in 1972, and is used for surgical anasthesia in Russia. Phenaridine has similar effects to fentanyl. In rat studies, it was less potent than fentanyl.
Human cord blood hematopoietic progenitor cell
go.drugbank.com/drugs/DB11054ApprovedHemacord is marketed in the U.S. as an allogeneic cord blood hematopoietic progenitor cell therapy for intravenous use. … After the first cord blood transplant in 1988 in a patient with Fanconi anemia [A32220], the use of umbilical cord blood transplantation was increased in clinical settings.
GR270773
go.drugbank.com/drugs/DB06427InvestigationalGR270773, was investigated in two clinical trials for its potential to treat sepsis: NCT00158769 (completed, comparing the effects of infusion between healthy adults and those with damaged livers) and
G207
go.drugbank.com/drugs/DB05827InvestigationalThese viruses are specific herpes simplex viruses, or HSVs, generally known as the cause of cold sores. … MediGene uses these viruses, however, in a modified and "disarmed" form in order to make them utilizable as a therapeutic agent in humans.
Methscopolamine
go.drugbank.com/drugs/DB11315ApprovedThe oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Felypressin
go.drugbank.com/drugs/DB00093InvestigationalA synthetic nonapeptide comprising cysteinyl, phenylalanyl, phenylalanyl, glutaminyl, asparaginyl, cysteinyl, prolyl, lysyl, and glycinamide residues in sequence, with a disulfide bridge joining the two cysteine residues. Its antidiureti...