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Displaying results 3761 - 3770 of 10000 in total
  1. Drug

    CT-011

    go.drugbank.com/drugs/DB05916
    Investigational

    CT-011 is a humanized monoclonal antibody directed against a B7 family-associated protein, in patients with advanced haematological malignancies. … It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activities.

  2. Drug

    Altanserin

    go.drugbank.com/drugs/DB19972
    Investigational

    Altanserin is under investigation in clinical trial NCT03970239 (Serotonin in Impulse Control Disorders in Parkinson's Disease). Altanserin has a monoisotopic molecular weight of 411.14 Da. … Altanserin is a small molecule drug. The usage of the INN stem '-anserin' in the name indicates that Altanserin is a serotonin receptor antagonist.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    IGN301

    go.drugbank.com/drugs/DB05117
    Experimental

    IGN301 is a cancer vaccine based on an anti-idiotypic antibody which provokes an immune response to Lewis Y. … Lewis Y is a carbohydrate molecule expressed on the surface of tumor cells of epithelial origin (e.g. lung, intestinal, breast, prostate or ovarian cancers).

  4. Drug

    Vidarabine

    go.drugbank.com/drugs/DB00194
    ApprovedWithdrawn

    It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the … A nucleoside antibiotic isolated from Streptomyces antibioticus.

    International brands: Arasena-AProducts: Vira-A
  5. Drug

    INNO-305

    go.drugbank.com/drugs/DB06025
    Investigational

    The vaccine is a polyvalent Wilms tumor gene 1 (WT1) peptide analog vaccine. … INNO-305 is an investigational vaccine developed by Innovive Pharmaceuticals for the treatment of patients with acute myeloid leukemia in complete remission.

  6. Drug

    Diiodohydroxyquinoline

    go.drugbank.com/drugs/DB09115
    Approved

    Diiodohydroxyquinoline, also known as uidoquinol and iodoquinol, is a quinoline derivative that can be used in the treatment of amoebiasis. The exact mechanism of action is unknown. … Iodoquinol is not currently available in any FDA-approved products.

    Mixtures: Alcortin A, Alcortin A
  7. Drug

    Sulodexide

    go.drugbank.com/drugs/DB06271
    ApprovedInvestigationalWithdrawn

    Sulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).

  8. Drug

    Propyl Gallate

    go.drugbank.com/drugs/DB12450
    Investigational

    Propyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects).

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    NBI-6024

    go.drugbank.com/drugs/DB05819
    Investigational

    NBI-6024 is an altered peptide ligand that is designed to cause an immune response which result in preservation of beta-cell function and endogenous insulin production.

  10. Drug

    Propidium

    go.drugbank.com/drugs/DB02166
    Experimental

    Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes … with cholinesterase which it inhibits.

    Categories: Compounds used in a research, industrial, or household setting