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Displaying results 3781 - 3790 of 10000 in total
  1. Drug

    Deucravacitinib

    go.drugbank.com/drugs/DB16650
    ApprovedInvestigational

    Unlike other Janus kinase 1/2/3 inhibitors that bind to the conserved active domain of these non-receptor tyrosine kinases, deucravacitinib binds to the regulatory domain of TYK2 with high selectivity … Deucravacitinib is a novel oral selective tyrosine kinase 2 (TYK2) inhibitor.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: SOTYKTU 6 mg film coated tablets, SOTYKTU® 6MG TABLETAS RECUBIERTAS
  2. Drug

    TSHA-118

    go.drugbank.com/drugs/DB16996
    Experimental

    TSHA-118 is a self-complementary AAV9 gene replacement therapy designed to express a human codon-optimized CLN1 transgene for the treatment of CLN1 disease.

  3. Drug

    Foxy-5

    go.drugbank.com/drugs/DB13034
    Investigational

    Foxy-5 has been used in trials studying the treatment of Prostate Cancer, Colorectal Cancer, Metastatic Colon Cancer, Metastatic Breast Cancer, and Metastatic Prostate Cancer.

    Synonyms: Foxy-5
  4. Drug

    MK-8776

    go.drugbank.com/drugs/DB11899
    Investigational

    Sch 900776 has been used in trials studying the treatment of Neoplasms, Hodgkin Disease, Adult Erythroleukemia, Lymphoma, Non-Hodgkin, and Myelogenous Leukemia, Acute, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Inclacumab

    go.drugbank.com/drugs/DB12246
    Investigational

    Inclacumab has been used in trials studying the treatment and prevention of Myocardial Infarction, Peripheral Arterial Disease (PAD), and Coronary Heart Disease, Graft Occlusion, Vascular.

  6. Drug

    Tetrahydrouridine

    go.drugbank.com/drugs/DB12484
    Investigational

    Tetrahydrouridine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Sickle Cell Disease, and Head and Neck Cancer, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Molgramostim

    go.drugbank.com/drugs/DB12525
    Investigational

    Molgramostim has been used in trials studying the treatment of Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and Autoimmune Pulmonary Alveolar Proteinosis

  8. Drug

    AFN-1252

    go.drugbank.com/drugs/DB12658
    Investigational

    AFN-1252 has been used in trials studying the treatment of Cellulitis, Burn Infection, Wound Infection, Cutaneous Abscess, and Skin and Subcutaneous Tissue Bacterial Infections.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    Mirodenafil

    go.drugbank.com/drugs/DB11792
    Investigational

    Mirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    4D-310

    go.drugbank.com/drugs/DB18323
    Investigational

    4D-310 is a adeno-Associated Virus Serotype 2 capsid variant (4D-C102) carrying a transgene encoding a codon-optimized human alpha-galactosidase A gene