Tetrahydrouridine

DB12484InvestigationalSmall molecule

Tetrahydrouridine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Sickle Cell Disease, and Head and Neck Cancer, among others.

Chemical structure of Tetrahydrouridine
Formula / weight
C9H16N2O6 · 248.235 g/mol (avg)

Resolves to

Compound
UNII0NIZ8H6OL8CAS18771-50-1ChEMBLCHEMBL2311128PubChem29243
Structure
InChIKeyUCKYOOZPSJFJIZ-XVKVHKPRSA-NSMILESOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CCC(O)NC1=O
Targets
P32320CDA

What you can answer from here — as of April 02, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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19Clinical trialsPhase, status and sponsor resolved per trial
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Tetrahydrouridine, and which of those have an active Phase 3 trial?

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