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Displaying results 3781 - 3790 of 10000 in total
  1. Drug

    Pralatrexate

    go.drugbank.com/drugs/DB06813
    ApprovedInvestigational

    [A246703] As such, pralatrexate is thought to have a better therapeutic window compared to other antifolate analogs due to the novel target of RFC. … [A246693] Compared to methotrexate, pralatrexate has better accumulation in cancer cells.

    Synonyms: (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid, (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acidCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    CHIR-124

    go.drugbank.com/drugs/DB06852
    Experimental

    CHIR-124 is a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo.

    Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide

    go.drugbank.com/drugs/DB06941
    Experimental

    (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide is a solid. This compound belongs to the phenylpiperazines. … These are compounds containing a phenylpiperazine skeleton, which consists of a piperazine bound to a phenyl group. This drug targets the protein S100B.

    Synonyms: (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide
  4. Drug

    N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide

    go.drugbank.com/drugs/DB06942
    Experimental

    N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. This compound belongs to the alpha amino acid amides. These are amide derivatives of alpha amino acids.

    Synonyms: N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide
  5. Drug

    JNJ-27390467

    go.drugbank.com/drugs/DB06962
    Experimental

    JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase.

  6. Drug

    Paratoulene phosphate

    go.drugbank.com/drugs/DB04495
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    5-Nitroindazole

    go.drugbank.com/drugs/DB04534
    Experimental

    Synonyms: 5-Nitroindazole, 5-Nitro-1H-indazoleCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  8. Drug

    1-benzylimidazole

    go.drugbank.com/drugs/DB04581
    Experimental

    1-benzylimidazole, an N-imidazole derivative, has been shown to have strong cardiotonic activity.

    Synonyms: 1-benzylimidazole, 1-benzyl-1H-imidazoleCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Octylphenoxy polyethoxyethanol

    go.drugbank.com/drugs/DB04682
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Estrane-3,17-dione

    go.drugbank.com/drugs/DB04693
    Experimental

    Estrane-3,17-dione is a potent inhibitor of isomerase.