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Displaying results 371 - 380 of 5504 in total
  1. Drug

    Zidovudine

    go.drugbank.com/drugs/DB00495
    ApprovedInvestigational

    It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS.

    Mixtures: Zidovex LN (Lamivudine 150mg, Zidovudine 300mg, Nevirapine 200mg Tablets), COMBIVIR 150MG/300MGProducts: ZIDO H ® SOLUCION ORAL 10MG/ML, ZIDOVEX 50mg/5ml (Zidovudine Oral Solution 50 mg/5ml)
  2. Drug

    Nicotine

    go.drugbank.com/drugs/DB00184
    ApprovedInvestigational

    It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission.

    Products: Nicorette Invisi Transdermal Patch 10mg/16 hours, NIQUITIN 14MG TRANSDERMAL PATCH
  3. Drug

    Ranitidine

    go.drugbank.com/drugs/DB00863
    ApprovedWithdrawn

    Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulc...

    Products: RANITIDINA 50MG EN SODIO CLORURO 0.7 % POR 50 ML INFUSION, RANIDURA T 150MG
  4. Drug

    Ticlopidine

    go.drugbank.com/drugs/DB00208
    Approved

    It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. … The FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they

    Products: TICLOPIDIN - CT 250MG FTA, TICLOPIDINA EG
  5. Drug

    Rizatriptan

    go.drugbank.com/drugs/DB00953
    ApprovedInvestigational

    Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT<sub>1B and 5-HT1D</sub> receptor agonist.

    Products: RIZATRIPTAN EG, MAXALT 10MG
  6. Drug

    Perindopril

    go.drugbank.com/drugs/DB00790
    ApprovedInvestigational

    It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration.

    Mixtures: COVERAM Tablet 10mg/10mg, COVERAM 10MG/10MG TABLETProducts: COVERSYL 10mg tablet, COVERSUM ARGININ 10MG FTA
  7. Drug

    Gefitinib

    go.drugbank.com/drugs/DB00317
    ApprovedInvestigational

    It is marketed by AstraZeneca under the trade name Iressa.

    Products: GEFITINIB EG, IRESSA 250MG
  8. Drug

    Selegiline

    go.drugbank.com/drugs/DB01037
    ApprovedInvestigationalVet approved

    It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. … It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.

    Products: SELEGILIN STADA 10MG, SELEGILIN HEXAL 10MG TABL
  9. Drug

    Pantoprazole

    go.drugbank.com/drugs/DB00213
    ApprovedInvestigational

    [A177271][F4498] Its efficacy is considered similar to other medications within the PPI class including [omeprazole], [esomeprazole], [lansoprazole], [dexlansoprazole], and [rabeprazole]. … It can also be found in quadruple regimens for the treatment of _H. pylori_ infections along with other antibiotics including [amoxicillin], [clarithromycin], and [metronidazole], for example.

    Products: PANTOPRAZOL - CT 20MG, PANTOPRAZOL - CT 40MG
  10. Drug

    Brexpiprazole

    go.drugbank.com/drugs/DB09128
    ApprovedInvestigational

    It also displays stronger antagonism at the 5-HT1A and 5-HT2A receptors.[A182186, A38385, A259661] Brexpiprazole was first approved by the FDA on July 10, 2015. … It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors.

    Products: Rexulti 1mg film-coated tablets, Rexulti 2mg film-coated tablets