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Displaying results 371 - 380 of 10000 in total
  1. Drug

    Purine Riboside-5'-Monophosphate

    go.drugbank.com/drugs/DB03726
    Experimental

    Synonyms: Purine Riboside-5'-Monophosphate
  2. Drug

    5-methyl-2'-deoxypseudouridine

    go.drugbank.com/drugs/DB03763
    Experimental

    Synonyms: 5-methyl-2'-deoxypseudouridine
  3. Drug

    Sildenafil

    go.drugbank.com/drugs/DB00203
    ApprovedInvestigational

    In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850 … Regardless, sildenafil, among a variety of other similar or related PDE5 inhibitors, has become a common and effective treatment for erectile dysfunction and since its formal approval for medical use in

    Mixtures: DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET, DAPOKSEL 30 MG/50 MG FILM TABLET ,6 FILM TABLETCategories: Phosphodiesterase 5 Inhibitors, Cytochrome P-450 Substrates
  4. Drug

    Tegaserod

    go.drugbank.com/drugs/DB01079
    ApprovedWithdrawn

    mechanism of action of acting on serotonin-4 (5-HT(4)) receptors in smooth muscle cells and in the gastrointestinal wall to facilitate actions like esophageal relaxation, peristaltic gut movement, and … in female patients less than 65 years of age and whom are considered to be at a lower risk of a cardiovascular event than the broader population.

    Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsSynonyms: 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidine
  5. Drug

    Tibolone

    go.drugbank.com/drugs/DB09070
    ApprovedInvestigational

    Tibolone is approved in 90 countries to manage menopausal symptoms and in 45 countries to prevent the development of osteoporosis [L1876]. … Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha [L1874].

    Synonyms: 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-oneProducts: TIBONELLA® TABLETAS 2.5 MG, TINOX® 2.5 MG COMPRIMIDOS
  6. Drug

    19-Nor-5-androstenedione

    go.drugbank.com/drugs/DB01443
    ExperimentalIllicit

    19-Nor-5-andorstenedione is a prohormone which has the potential to affect bodily levels of testosterone once metabolized in vivo. … It is regulated in the United States as a schedule III controlled substance, and prohibited by the World Anti-Doping Agency for use in competitive sports.

    Synonyms: estr-5-ene-3,17-dione, 19-Nor-5-androstenedione
  7. Drug

    2'-fluoro-5-ethylarabinosyluracil

    go.drugbank.com/drugs/DB13030
    Investigational

    2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-fluoro-5-ethylarabinosyluracil, 2'-Fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil
  8. Drug

    Sertindole

    go.drugbank.com/drugs/DB06144
    ApprovedWithdrawn

    Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. … It is a phenylindole derivative used in the treatment of schizophrenia.

    Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsSynonyms: 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one
  9. Drug

    5-N-Allyl-arginine

    go.drugbank.com/drugs/DB03892
    Experimental

    Synonyms: 5-N-Allyl-arginine
  10. Drug

    5-Phenylsulfanyl-2,4-Quinazolinediamine

    go.drugbank.com/drugs/DB04163
    Experimental

    Synonyms: 5-Phenylsulfanyl-2,4-Quinazolinediamine