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Irinotecan
go.drugbank.com/drugs/DB00762ApprovedInvestigationalThis leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] … [L50186] The active metabolite SN-38 is also a potent inhibitor of DNA topoisomerase I.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl, )ethyl)piperidine-1-carboxylate(E)-(4S,6S)-8-METHYL-6-((S)-3-METHYL-2-{(S)-2-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID BENZYL ESTER
go.drugbank.com/drugs/DB04595ExperimentalSynonyms: (E)-(4S,6S)-8-METHYL-6-((S)-3-METHYL-2-{(S)-2-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID BENZYL ESTERL-valinol
go.drugbank.com/drugs/DB04383ExperimentalSynonyms: (S)-(+)-2-Amino-3-methyl-1-butanol, (2S)-2-amino-3-methylbutan-1-olS-{2-[(2-chloro-4-sulfamoylphenyl)amino]-2-oxoethyl} 6-methyl-3,4-dihydroquinoline-1(2H)-carbothioate
go.drugbank.com/drugs/DB08494ExperimentalSynonyms: S-{2-[(2-chloro-4-sulfamoylphenyl)amino]-2-oxoethyl} 6-methyl-3,4-dihydroquinoline-1(2H)-carbothioate3-Phosphono-D-alanine
go.drugbank.com/drugs/DB03292ExperimentalSynonyms: (S)-2-Amino-3-phosphonopropanoic acid, D-2-Amino-3-phosphonopropionic acidS-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate
go.drugbank.com/drugs/DB08585ExperimentalSynonyms: S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioateL-Glutamine
go.drugbank.com/drugs/DB00130ApprovedInvestigationalNutraceuticalA non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. … It is the principal carrier of nitrogen in the body and is an important energy source for many cells.
Synonyms: (S)-2,5-diamino-5-oxopentanoic acid, (2S)-2-amino-4-carbamoylbutanoic acidInternational brands: L-Glutamine PowerAlbendazole oxide
go.drugbank.com/drugs/DB13871ExperimentalSynonyms: Albendazole S-oxide, Methyl 5-(propylsulfinyl)-2-benzimidazolecarbamateCategories: Heterocyclic Compounds, 2-RingS-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate
go.drugbank.com/drugs/DB08586ExperimentalSynonyms: S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioateAdinazolam
go.drugbank.com/drugs/DB00546ExperimentalAdinazolam (Deracyn®) is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative, and antidepressant properties.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: 8-Chloro-1-((dimethylamino)methyl)-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine