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Displaying results 371 - 380 of 10000 in total
  1. Drug

    Pancrelipase

    go.drugbank.com/drugs/DB00085
    ApprovedInvestigational

    Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. … [L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.

    Products: KREON 20000PH EU LI EI HKM, PANZYTRAT OK MA RE MICROTA
  2. Drug

    Hydroxyprogesterone caproate

    go.drugbank.com/drugs/DB06789
    Approved

    FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy … Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999.[L46118] The U.S.

    Products: PROLUTON DEPOT 250MG INJ (1ML AMP), PROLUTON DEPOT 500 MG/2ML IM ENJEKSIYONLUK COZELTI ICEREN AMPUL, 50 ADET
  3. Drug

    Flupentixol

    go.drugbank.com/drugs/DB00875
    ApprovedInvestigationalWithdrawn

    It is approved for use in Canada and other countries around the world, but not in the US. … Flupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms.

    Products: Fluanxol Depot Inj 20mg/ml, Fluanxol Depot Inj 100mg/ml
  4. Drug

    Cyclophosphamide

    go.drugbank.com/drugs/DB00531
    ApprovedInvestigational

    It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. … Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide.

    Synonyms: N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxideMixtures: Procytox for Injection 2000mg Pws IV
  5. Drug

    Esomeprazole

    go.drugbank.com/drugs/DB00736
    ApprovedInvestigational

    [A177571] Rapid discontinuation of PPIs such as esomeprazole may cause a rebound effect and a short term increase in hypersecretion. … [A177577, A177580] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread.

    Products: ESOMEPRAZOLO CIPLA EUROPE, ESOMEPRAZOLO SUN PHARMACEUTICAL INDUSTRIES (EUROPE) BV
  6. Drug

    Vitamin E

    go.drugbank.com/drugs/DB00163
    ApprovedInvestigationalNutraceuticalVet approved

    In 1922, vitamin E was demonstrated to be an essential nutrient[A32448]. … Though this research is so far inconclusive, vitamin E remains a popular supplement and is generally considered safe by the FDA[FDA Label].

    Mixtures: Formula F L W, L-Methyl PNV DHACategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Docetaxel

    go.drugbank.com/drugs/DB01248
    ApprovedInvestigational

    [A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and promote to cell death. … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel].

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol, N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel
  8. Drug

    Darbepoetin alfa

    go.drugbank.com/drugs/DB00012
    ApprovedInvestigational

    Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.

    Products: ARANESP 500UG ILO IN FER, ARANESP 100UG INJ LSG
  9. Drug

    Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10769
    ApprovedInvestigational

    Synonyms: Japanese encephalitis virus strain SA 14-14-2 antigen (formaldehyde inactivated)Products: IXIARO Suspension for Injection 0.5ml in pre-filled syringe
  10. Drug

    Aminocaproic acid

    go.drugbank.com/drugs/DB00513
    ApprovedInvestigational

    An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.

    International brands: Kai Nai YinProducts: Amicar Inj 250mg/ml, Amicar Injection - Liq IV 250mg/ml