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Tiopronin
go.drugbank.com/drugs/DB06823ApprovedIt is similar to d-penicillamine in use and efficacy, but offers the advantage of far less adverse effects. … As cystinuria is a relatively rare disease, tiopronin is classified as an orphan drug and is not patented in the United States.
Categories: Reducing and Complexing Thiol, Amino Acids, Peptides, and ProteinsPoloxamer 188
go.drugbank.com/drugs/DB11333ApprovedP188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the blood before transfusions, however it is no longer available in any approved products [A27217]. … There is an evidence of P188 increasing the structural stability and resealing of the plasma membrane via direct incorporation into the phospholipid bilayer [A27217].
Categories: Compounds used in a research, industrial, or household settingDiphenidol
go.drugbank.com/drugs/DB01231ApprovedWithdrawnDiphenidol is an antiemetic agent used in the treatment of vomiting and vertigo. Diphenidol overdose may result in serious toxicity in children.
Gefapixant
go.drugbank.com/drugs/DB15097ApprovedIt received approval in both Japan and Switzerland in 2022 for the treatment of adult patients with RCC and UCC, and received subsequent approval in the EU in September 2023 for the same indications. … or unexplained chronic cough (UCC) when no diagnosable cause for the cough can be determined.
Categories: Cough and Cold PreparationsZidebactam
go.drugbank.com/drugs/DB13090ApprovedZidebactam is a diazabicyclooctane that acts both as a beta-lactamase inhibitor and as an antibacterial in its own right, selectively binding penicillin-binding protein 2. … [L63350] It is available only in fixed combination with [cefepime], which binds PBP3 and PBP1a/b.
Stanozolol
go.drugbank.com/drugs/DB06718ApprovedVet approvedStanozolol is derived from testosterone, and has been abused by several high profile professional athletes. … Stanozolol is a synthetic anabolic steroid with therapeutic uses in treating hereditary angioedema.
Categories: Alimentary Tract and Metabolism, Hormones, Hormone Substitutes, and Hormone AntagonistsBitolterol
go.drugbank.com/drugs/DB00901ApprovedWithdrawnBitolterol mesylate was used to treat bronchospasms in asthma and COPD. It is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.
Benzonatate
go.drugbank.com/drugs/DB00868ApprovedBenzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age. … [A189519] It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs and pleura involved in the cough reflex.
Categories: Cough and Cold PreparationsSynonyms: nonaethyleneglycol monomethyl ether p-n-butylaminobenzoateAlbumin Aggregated
go.drugbank.com/drugs/DB14230ApprovedAlbumin aggregated is an ingredient in the DRAXIMAGE MAA kit for the preparation of technetium tc99m albumin aggregated injection. … [L12816] This imaging agent is used to assess lung perfusion and for the evaluation of peritoneovenous (LeVeen) shunt patency.
Sibeprenlimab
go.drugbank.com/drugs/DB18919ApprovedInvestigationalSibeprenlimab is a Proliferation Inducing Ligand (APRIL) blocker.[L54633] APRIL is a member of the tumour necrosis factor superfamily that regulates and modulates activated B cells. … [L54633] On November 25, 2025, sibeprenlimab was granted accelerated approval by the FDA to reduce proteinuria in adults with primary IgAN at risk for disease progression.[L54628]
Categories: Amino Acids, Peptides, and Proteins